ID   A0A388JMV2_CHABU        Unreviewed;       847 AA.
AC   A0A388JMV2;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=CBR_g32144 {ECO:0000313|EMBL:GBG59127.1};
OS   Chara braunii (Braun's stonewort).
OC   Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC   Chara.
OX   NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG59127.1, ECO:0000313|Proteomes:UP000265515};
RN   [1] {ECO:0000313|EMBL:GBG59127.1, ECO:0000313|Proteomes:UP000265515}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S276 {ECO:0000313|EMBL:GBG59127.1,
RC   ECO:0000313|Proteomes:UP000265515};
RX   PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA   Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA   Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA   Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA   Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA   Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA   Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA   Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA   Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA   Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA   Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA   Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA   Rensing S.A.;
RT   "The Chara Genome: Secondary Complexity and Implications for Plant
RT   Terrestrialization.";
RL   Cell 174:448-464(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBG59127.1}.
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DR   EMBL; BFEA01000003; GBG59127.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A388JMV2; -.
DR   EnsemblPlants; GBG59127; GBG59127; CBR_g32144.
DR   Gramene; GBG59127; GBG59127; CBR_g32144.
DR   Proteomes; UP000265515; Unassembled WGS sequence.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT   DOMAIN          500..698
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          300..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        322..350
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   847 AA;  94178 MW;  8D0C23712B74A3C8 CRC64;
     MVEVLASLDA PGSRQYPLRY PWLGAALIFL RETDHWQRKV PTWRHGTQGP AAGADSTLAV
     NSNEVGTSAS AAAPGSEPAA VGPSYAGPYV DRKLVQMPSK YDGKEDIESW IGSMRAYFEI
     LGTQTETQAV IMGMNVEPVV RGFLEVQATR AGFPKAALAK WLRATPVASL EELLTSEYLD
     PHVAAKARIQ LDKVKHSKWN GSMKSLQTYL SKLLATPGLE LSPQSCLDVV KGAVPTHFTS
     RLGTGYIAYT NWLALMKDVV GLEAMDLVST AGSKKPMGGR RFKGNNRLAV HDLLEAEEGA
     DAVDPTLGDD QEQDSDTAWK PESGVESDSA NSTAREAGSV DDQQPSLAAQ PSVEDKVAAS
     NVLYGEPWEE SEMIDFHYHL EHWPEMKQQR AQGTVKLIFF KLLINHHYLR GATANFMSPH
     GIRKVGLGMK QVALQNPCRT QVGNKEVVSS THAVKGVRTT FDKGKTVTHA LNFFALDKCP
     LDTVLGLGWL QSQCEWTKWK ESLFMVKDAK GNELPVLLDE KRESPVTFLN ALKFCKKWRK
     HKEEKQLYVA FVRPAHVPST FAANTTTTSM DESTSGGCKV FSKIDLKSGY HQIEVDPADQ
     HKTAFKTRDG FYEFTVMPFG LTNAPATFRS LMDKVLREQS GRFVVVYLDD ILIFSKSMEE
     HLEHLEEVLA VLKKTQLHLN FAKSEFGKDS VIYLGHRLSV AGLEPEATKI EVIRDWPHPV
     NIRKLRSFLG LASYYRKFVP RFSIIARPLS QLTSKKVSYS WDVACSEAFQ ALKEALVSYP
     VLRIADPKLT FVVTTDASQY GIGAVLQQDD GDGLRPLEYY SKRMPSVKVA TSTYMRELYA
     LRMALDH
//