ID   A0A388JRE4_CHABU        Unreviewed;       910 AA.
AC   A0A388JRE4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=CBR_g4342 {ECO:0000313|EMBL:GBG60384.1};
OS   Chara braunii (Braun's stonewort).
OC   Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC   Chara.
OX   NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG60384.1, ECO:0000313|Proteomes:UP000265515};
RN   [1] {ECO:0000313|EMBL:GBG60384.1, ECO:0000313|Proteomes:UP000265515}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S276 {ECO:0000313|EMBL:GBG60384.1,
RC   ECO:0000313|Proteomes:UP000265515};
RX   PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA   Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA   Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA   Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA   Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA   Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA   Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA   Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA   Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA   Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA   Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA   Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA   Rensing S.A.;
RT   "The Chara Genome: Secondary Complexity and Implications for Plant
RT   Terrestrialization.";
RL   Cell 174:448-464(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBG60384.1}.
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DR   EMBL; BFEA01000010; GBG60384.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A388JRE4; -.
DR   EnsemblPlants; GBG60384; GBG60384; CBR_g4342.
DR   Gramene; GBG60384; GBG60384; CBR_g4342.
DR   Proteomes; UP000265515; Unassembled WGS sequence.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR33064; POL PROTEIN; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT   DOMAIN          499..678
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          90..167
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        132..149
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   910 AA;  103257 MW;  BEEA3783DB096BAC CRC64;
     MTQGNTSTRD WPLEWQKIAA TPDLDLPFSH LRREFYNRSC AALSLALGDG EQYATFAEII
     DKAREIIKTN RAAAHEKSAW QPTYVEKVKT GPRPQHVAAV QSDNIVEDPA TTQASREGDH
     RWLLSSREAT TSPEETGRRK PHRRPETDSQ RYGCAGGEAT PPLTPPDSAA LLASSYTSGE
     DANVANSRYT YEDYVIHLVP PLDQPLHVQQ STACTVSPPS ATNSAASPPS IAGDLTSWSR
     LEELDPLTFA DFQWMPLPRS GRLPKPHCNV LMAQLRDYLH TAVPTPLMDA GVEVVDLHDY
     IAKINREFKT QRYDDIDAPL LYVRIQIGVA TCNALINCGA SRNYMSQDFM VRIGLGPRVR
     RKSQPTQVTL VDGHTPKSID RCIDDIPVYF APHASEAVSF DIFDTKFDMI LGMSWLRSED
     HPVNFYHRTV HIRDRNGVQV PCTVPLPHPS ISCHVVSAAS MQASIMRDDI EEMGMCFLHA
     LPPHDASSTD SSSDPRITEL LDFYGEVSSP YGAPVLFVRK KNKDLRLCID YRKLNVQTVK
     NAGPLPRIDD LLERLGGAKF FSKLDLKSGY HQLEIRQEDR YKTAFKTRYG HFEWLVMPFG
     LTNAPTTFQA AMTTEFRHML DRFVLIYLDD ILVYSRSLDE HVEHLRTVLE RLRQAKYKAN
     RDKCEFARQE LEYLGHYVTP QGICPLADKI EAIRVWPEPT NTTDVHSFMG LAGYYQRFIT
     GYSRIAAPMT RLQSPKVPFV FDDDARRPFQ ALKTAMLMAP VLSIYDPTLP TRVTTDASGY
     GIGAVLEQHD GDDWHPVEYF SHKVPPINSR DNARKKELLA FVTALKRWRH FLLRRRRFTW
     VADNKPLTSY KTQDTVSSTI GRWMYFIDQF DFTPKHLPGL SNRAKTRSLR YDTSCLRIRR
     GTPATLHPGI
//