ID   A0A388JRR6_CHABU        Unreviewed;      1186 AA.
AC   A0A388JRR6;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|Pfam:PF00078};
GN   ORFNames=CBR_g5665 {ECO:0000313|EMBL:GBG60491.1};
OS   Chara braunii (Braun's stonewort).
OC   Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC   Chara.
OX   NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG60491.1, ECO:0000313|Proteomes:UP000265515};
RN   [1] {ECO:0000313|EMBL:GBG60491.1, ECO:0000313|Proteomes:UP000265515}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S276 {ECO:0000313|EMBL:GBG60491.1,
RC   ECO:0000313|Proteomes:UP000265515};
RX   PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA   Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA   Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA   Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA   Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA   Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA   Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA   Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA   Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA   Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA   Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA   Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA   Rensing S.A.;
RT   "The Chara Genome: Secondary Complexity and Implications for Plant
RT   Terrestrialization.";
RL   Cell 174:448-464(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBG60491.1}.
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DR   EMBL; BFEA01000011; GBG60491.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A388JRR6; -.
DR   EnsemblPlants; GBG60491; GBG60491; CBR_g5665.
DR   Gramene; GBG60491; GBG60491; CBR_g5665.
DR   Proteomes; UP000265515; Unassembled WGS sequence.
DR   GO; GO:0005869; C:dynactin complex; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR028133; Dynamitin.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF13650; Asp_protease_2; 1.
DR   Pfam; PF04912; Dynamitin; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT   DOMAIN          1068..1184
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          567..616
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          710..730
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          301..346
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1186 AA;  133150 MW;  07402C1FE431190A CRC64;
     MMAFNHEWQY QEAEVFESPD DPEDAPDKNP VYCQPQPQAV FEDEGIDTTG FSASEAFELF
     STKSHLLTGI NSRLSCGKSI KKSIHQNQAS SRGQRSSVPE DFYESPAQRY LRLQSEIQAL
     QEELECLCSN DEGSLRSKGG STVSSKDVGR LQQELSSLAE DRRWRVLLNP FMSDPSVMES
     FELQHMLSKR LLSELECVRA NTNAVNKEEQ ASADAEDVSK EAKKSPAVTY EVYYTPTTDV
     SVAQVKELMD LERRITRLEK SVGGQFSQGG SLLDLHAGMR DLEKKIDMLD PQRLAALDGT
     LENLNLKMAA TLEMKQELAE IDSSTTTELD EKVNRIFEKM EECEAEASQL PEILEFLQLT
     STMYTKNFTL CEQVDRIQHE QNHIVNSIRL QKELIQKAVP GPDAGASSSA PPSRQLEERV
     DHVVAMLSDI STFAAPTTIS SQLDALKTEV QQLQSTNTDG NPKQYKMPTF QLERFDDYTH
     QDPVLWWEAF TTQLQILPVA KHASCAALSQ ALGDREQYAS FAEIIDKARE IIKTNRSAAH
     EKSTWQPTYV EKVRTGPRQQ QFAAVQLDSG EDPAATSASR EGDQVAAVQP RSIKPRVNGK
     AKPASQAENG QPAPPWVKFG LTETEYKYRN RYGCCYWCNS TKHKTSICQD QAKEDVQSHS
     AALLAASYTS GEDAHVASPW YTYEDYAVQL VPPLDQPLHV QYSTACTVSS PSATDSAASS
     SSTAGDSTSW SSLEELNPLT FEDFQWMPLP QSGRLPKPHC NVLKAQLRDY LHTAVPTPLM
     DAGVEVVDLY AYIAKIDREL KTQRYDDIDA PLLYVRIQIG EATCSALFDC GASRNYMSQD
     FMVRAGLGPR VRRKSQPTQV TLADGHTHKS IDRCIDDVPV YFAPHASEAV SFDILDTKFD
     MILGMSWLRS EDHPVNFYRR TVHVRDRNGV LVPCTVAPPH PSVSCHVVSA ASMRASIIRD
     DIEEMGVCFL LALPPQDASS TDSSSDPRIT ELLDAYSDVF EGPHGVVPDR PIRHKIILED
     GAVPPRGCIY RMSEEELSVL RAQLDDLLEK GWIRPSSLPY GAPVLFVRKK NKDLQLCIDY
     RKLNAQTIRN AGPLPRIDDL LERLGGAKFF SKLDLKSGYH QLDIRKEDRY KTAFKTRYGR
     FEWLVMPFGF TNAPSTFQAA MTTEFRHMLD RYVLIYLDDI LVYRRS
//