ID A0A388K0B9_CHABU Unreviewed; 610 AA.
AC A0A388K0B9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Mediator of RNA polymerase II transcription subunit 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBR_g38095 {ECO:0000313|EMBL:GBG63477.1};
OS Chara braunii (Braun's stonewort).
OC Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC Chara.
OX NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG63477.1, ECO:0000313|Proteomes:UP000265515};
RN [1] {ECO:0000313|EMBL:GBG63477.1, ECO:0000313|Proteomes:UP000265515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S276 {ECO:0000313|EMBL:GBG63477.1,
RC ECO:0000313|Proteomes:UP000265515};
RX PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA Rensing S.A.;
RT "The Chara Genome: Secondary Complexity and Implications for Plant
RT Terrestrialization.";
RL Cell 174:448-464(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the Mediator complex subunit 4 family.
CC {ECO:0000256|ARBA:ARBA00009626}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG63477.1}.
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DR EMBL; BFEA01000039; GBG63477.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A388K0B9; -.
DR STRING; 69332.A0A388K0B9; -.
DR EnsemblPlants; GBG63477; GBG63477; CBR_g38095.
DR Gramene; GBG63477; GBG63477; CBR_g38095.
DR OMA; GSTTRIW; -.
DR Proteomes; UP000265515; Unassembled WGS sequence.
DR GO; GO:0016592; C:mediator complex; IEA:InterPro.
DR GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR InterPro; IPR019258; Mediator_Med4.
DR PANTHER; PTHR13208; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4; 1.
DR PANTHER; PTHR13208:SF2; MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4; 1.
DR Pfam; PF10018; Med4; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000265515};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 115..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 331..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 495..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..44
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..82
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..367
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..535
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..569
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 610 AA; 63564 MW; 1ED8146108C9FC61 CRC64;
MREPLLMEDG IRGKPPSGSP LLLRTQSPPP PPPPPPPPPS PSPAAAAAAA AAAAAAPSGP
AAPLKNDNST AVELHNGSSF PSLLALSPKK RAETVLSEMN DLTQTVVNLI RTSGLGLQPS
VGSPKGGNFG TKVTGDDSAA RGGEGDTSLP QKRGAGELSD LGSGLDQGSH LVPRTKDILQ
KMTSYQDLLA STLQELADVD EPSEECSKAL SSQAVQNLSA LRDFGLLLRG VERVLESTLE
EFAAYKRPSL KRRGVESSQE DARMVVEGPS KQDLIDVQDL IAYAHKISYS TFAPPEFASG
QAPLRGFQPP APQDEHLRAS QLYLVKDVDL GIPPEPILKD EDEDEEEEEE EEEEEEEEDE
DDMEGEEEAA AGKLVTPLGA EKPPPDILPN IPPILPPGIG PVVPPPGWRP GMPVELPKDL
LSGLPGLPGL PGLPGLPGLP GLPGLPGLPP GLELPPMPPG WKPGDPVPID LPAPLPPVVP
SEVAVTVPRP AVAKEPVATA APTPSTATPT TTRPASRLTP PTAAPSSTAP QQLHPPTATP
AAPPPPVLQP RPPTATAAAQ LPPAPPAMPT TEAGVTHVPW VEIDLNPELS NSASSEPYSD
EFEDDDDDDD
//
