ID A0A388KG03_CHABU Unreviewed; 1317 AA.
AC A0A388KG03;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBR_g3670 {ECO:0000313|EMBL:GBG68971.1};
OS Chara braunii (Braun's stonewort).
OC Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC Chara.
OX NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG68971.1, ECO:0000313|Proteomes:UP000265515};
RN [1] {ECO:0000313|EMBL:GBG68971.1, ECO:0000313|Proteomes:UP000265515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S276 {ECO:0000313|EMBL:GBG68971.1,
RC ECO:0000313|Proteomes:UP000265515};
RX PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA Rensing S.A.;
RT "The Chara Genome: Secondary Complexity and Implications for Plant
RT Terrestrialization.";
RL Cell 174:448-464(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG68971.1}.
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DR EMBL; BFEA01000108; GBG68971.1; -; Genomic_DNA.
DR EnsemblPlants; GBG68971; GBG68971; CBR_g3670.
DR Gramene; GBG68971; GBG68971; CBR_g3670.
DR Proteomes; UP000265515; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.90.1420.10; Rubisco LSMT, substrate-binding domain; 1.
DR Gene3D; 3.90.1410.10; set domain protein methyltransferase, domain 1; 2.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR InterPro; IPR015353; Rubisco_LSMT_subst-bd.
DR InterPro; IPR036464; Rubisco_LSMT_subst-bd_sf.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF09273; Rubis-subs-bind; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF81822; RuBisCo LSMT C-terminal, substrate-binding domain; 1.
DR SUPFAM; SSF82199; SET domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265515};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 335..354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 471..586
FT /note="Rubisco LSMT substrate-binding"
FT /evidence="ECO:0000259|Pfam:PF09273"
FT DOMAIN 1041..1147
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
FT DOMAIN 1213..1306
FT /note="Reverse transcriptase/retrotransposon-derived
FT protein RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17919"
FT REGION 278..323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..993
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..321
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1317 AA; 147575 MW; 440D1899CC29809F CRC64;
MASTPWSGSS GLLSTSSAAI AILPSSDTWE LGRLCQPAGS VAALASTAAF PAKNSKARFF
QVLNRSSSTC HVARCSAIAY PTATWQQERA PHYYYRCMAI TSTMMRTKNT MGRRRRVSWD
HVDRATTATW HQNRARQPYG RCVQCQAAAA GASADWPRQQ NAAILLDWLE KKGLGGEQAG
DVALKIPEHL VVTGVDVASH PTISQAAAGR GDLIGLTLWL LAERALGEKS QWHPYVNIMP
KSTLSPLLWS AEERESLLKG SPVLAPCKAL TVAAGAAAAD GGDDDDDGIG NDDDDDDGGD
NHDDDDDDDD DDDDDDDDDE KMWDGKTMKM TTMKMMATAT MMMAIGLIAH IHLYYFSSNF
VQMMMMMMMM MISICCWSMK IGNLQVFPPE FFSLENFKAC FSVILSRVTY LPSADCFALI
PFDRLYQQGE QVNVTYGQDR PNSELLISYG FVDQKNLNDY LEVEVSLVGG DSMFSIKRQV
LEQWGLSTEQ SFPLFPDRFP SQLLSYLRLA RLTDAAKLPQ VVFDKDLVID QANEYEVLML
LMAECRGRLS KYSSTIDDDT RLLRDKNLGA KERVAAQLRL CEQGILTSTM TALRARLAPI
RGIPTKSGGL QDPNADIKQM FDQVEEVASA PRSSMGELHS RSTLQLQHDL SHNVKILAAA
VKVADNQLKQ LDARIATLEA RPPQAAPGCT PDMTDTTKQL NGRIDHVVNL IGDIGVFNGP
NTISSTVAAI KTDITKLQTK PDAATKSYKM PHFDISKFDD HNKTHALAWW ERFLAEASYR
TVPDDYLMKA LYLQLIGGAQ AWMNHLAATH TCTIAELHTH ITWKEFEQLW FTRFMVRNVV
KAAMKEVYTC SQGSMPTRDW TTKWQKIVTT PGFDLTFSNQ RSEFFSRSCL ELRSALGNEY
DYTSFQAILD RANLVIQTDD KTANEKQSQP HYVAKQGYQR PTHNHAVISE ATDDLHAAAA
SSSDGGIVAA LPPKRPKRVR KPKATQETAS TGTGQQPWTA YNITKEVYEL RQKYRYCLWC
NGVTHLTAQC PEKGKARVLR YHQIEIQPQD RYKTAFKTRY GHFEWVVMPF GLTNAPATFQ
AAMTTEFHDL LDRSVLIYLD DILVYSRTLD EHIVHXRVVL DRLRLAKYKA NLDKCEFAKQ
ELEYLGHFVT PKGIRPLADK IQAVVDWPEP RCTTDVRSFM GLAGYYQGFV ESYSKVATPL
SRLQSPKVPF EFDDAARGAF TTLKAAMQVA PALRIYDPTL PTQVTTDASG YGIGAVLEQC
HEDGWHPVEY FSQKVPLVNT LDDARKKELL AFVTVLKRWL HFLLGCRRLN RIRTTIR
//
