ID   A0A388KSB0_CHABU        Unreviewed;       638 AA.
AC   A0A388KSB0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|Pfam:PF00078};
GN   ORFNames=CBR_g12665 {ECO:0000313|EMBL:GBG72944.1};
OS   Chara braunii (Braun's stonewort).
OC   Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC   Chara.
OX   NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG72944.1, ECO:0000313|Proteomes:UP000265515};
RN   [1] {ECO:0000313|EMBL:GBG72944.1, ECO:0000313|Proteomes:UP000265515}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S276 {ECO:0000313|EMBL:GBG72944.1,
RC   ECO:0000313|Proteomes:UP000265515};
RX   PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA   Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA   Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA   Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA   Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA   Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA   Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA   Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA   Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA   Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA   Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA   Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA   Rensing S.A.;
RT   "The Chara Genome: Secondary Complexity and Implications for Plant
RT   Terrestrialization.";
RL   Cell 174:448-464(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBG72944.1}.
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DR   EMBL; BFEA01000174; GBG72944.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A388KSB0; -.
DR   EnsemblPlants; GBG72944; GBG72944; CBR_g12665.
DR   Gramene; GBG72944; GBG72944; CBR_g12665.
DR   Proteomes; UP000265515; Unassembled WGS sequence.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF08284; RVP_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT   DOMAIN          430..578
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|Pfam:PF00078"
FT   REGION          37..114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..92
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   638 AA;  72054 MW;  61D4D52D2B4839B5 CRC64;
     MRADQRLQAA ISKARDRAER RCRRDGVTVG LRVTVIYHET ESSTGTETRQ EQHNERDSGG
     ESEMSEADRE TDLRSWNRPE EIQRHHQATE PVEKGPEASS RQPTPRGRGT GGKQGCLQGP
     QCAALCAHIH TYLAFHAPPS SSTDDEAAVG DILAYVAKVA REFRLQRYDD NNALLLYVRI
     QVGQASCSAL LDSDATRNFI SQSFIQRAGL GAQVRRKPNP TAIKLADGQT QQLLDRYIEA
     VPVYFAPHAC EPVTFDVLDT DFDIIMGMPW LASADHTVNF HQRTLTVPDA FGVEVLCTIP
     LPHSSIRCQV VTAKSFRATW AYERTAEIGL CFLRAASTTE SSPTDLSLDP RVVRLLEEFT
     DIFEFPTGVV PDRPISHEII LEAGLVPPKG CIYRMSEEEL EVLRAQIDDL FDKGWIRPSS
     SPYGAPVLFV RKKNKDLHLC IHYRKLNAQT VKNAEPLSRI DDLLERLGGA NFFSKFDLKS
     GYHQISIRPQ DCYGHFEWIA MPFGLTNGPA TFQAAMTNEF HAMLDRFVLV DLDDILVYIR
     TLEDHLEHLR RVLETLRRAK YKANCDKCEF VRQELEYLDH FVTPEAISPL SDKIQAIQEW
     MEPKTVTNVR SFLGLAGYYQ PLHQGILEDR GSLIQALM
//