ID A0A388L0Y4_CHABU Unreviewed; 1187 AA.
AC A0A388L0Y4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN ORFNames=CBR_g21212 {ECO:0000313|EMBL:GBG75970.1};
OS Chara braunii (Braun's stonewort).
OC Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC Chara.
OX NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG75970.1, ECO:0000313|Proteomes:UP000265515};
RN [1] {ECO:0000313|EMBL:GBG75970.1, ECO:0000313|Proteomes:UP000265515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S276 {ECO:0000313|EMBL:GBG75970.1,
RC ECO:0000313|Proteomes:UP000265515};
RX PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA Rensing S.A.;
RT "The Chara Genome: Secondary Complexity and Implications for Plant
RT Terrestrialization.";
RL Cell 174:448-464(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG75970.1}.
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DR EMBL; BFEA01000234; GBG75970.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A388L0Y4; -.
DR EnsemblPlants; GBG75970; GBG75970; CBR_g21212.
DR Gramene; GBG75970; GBG75970; CBR_g21212.
DR Proteomes; UP000265515; Unassembled WGS sequence.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT DOMAIN 301..494
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 104..134
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 526..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 803..849
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1066..1187
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1084..1113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1128..1169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1187 AA; 133072 MW; 1C59022983F7E63B CRC64;
MLLHNAGRGP WNPPGRSFLS RTETVMFNKH DGTLILLLCD PACGNYEIIT CRNTGPRSIR
NRPNPGSFTI EESEGERWRL GRARSGREGE SIFPQPVRCW EGHGPGGHAR DGRSGCHPGL
EGAGSGMPRG RKVGVGISAP RQLKEPSISA STICEPAFLR RRLKQGSQRQ YKTVDKKCRP
VPVLVTEDKE AYYERERRLI RRMRESALAG PCRINEGNER ESIIGEPNFL LPRERALIVE
LMKRRHRAYA FSDEECGRLD VDKIPIIRNH TVPHEPWNMR RARFLNPDEE KKVVDYLDGK
IRTHVADYSS GPYASPWFCF IKPNGTLRWV QNLQRLNAVT VRDAGGLPNA DALSESCAGR
PIISLIDLYS GYDQFPVYPP DRPVMAMHTP RGLIHMNVAP QGWTNAEAMT QRAMIQVMQS
VSPYITQPYI DDLAMKGPAM KESDEVSPGV RLFVWKHTEG VEKVLGLLKK HNLTASGAKS
RHCKREATIL GFVCSEKSRR PDAKKTDKIT EWPILFHSIT DVRSFLGGGK GTRPPQRPLG
ASGGYERHEP RHRESTSVYD DGDIELFLDN FWDHARRMGW TVAETIERLR GAGRFEEPIT
RIRKEATTRQ EVEARMEELR PSPVGPDGRP IRLEIGNAAN FIPAFEWFMR GKGKEVIEVG
EDTPPQTPAV GFKLGDAPGS TRQAGKRLQT EEAPLPSSGK APSPEGDRAE RRRERAVVRR
EALILIDRHL AAHALEHPDL EEPVPAEPRQ EPCQPEKEME AEIPKKVELL TRKRAPAGET
VEEKRARRIR RIDEIWQERQ RLEAAGELPE QQQERQRSEA AGALPSQPPS APARAPEIPE
MWRDFWEQRG EKLPSPVRAG FGVARKAEER LDRKIKFLAN TTFDRHLLLE SDLAGKKMKE
ASHGVRLEAM EVEIQELRAL VVSQAAIIES LRQQTQGEVN NPESNRQGEK RQPGHGLPRQ
PSAAEPRQEP PMGRVILEPE EARAQRQAGR EAFEFKAPTE LSTLRVAAAG PIVPLAVEEG
LPPSSSEPAQ GSAEGSIGML LEAVHTMQEE MSLFSTEQRI EEPLEREMGN KAEGTIKSRL
QRMGTHEYGP EKIEEQPTAV PRETLERRPQ RLDTPEYVPA TRDLRSRLGS WATGSGSGGQ
VHGIEQQEFV STAAPRSEQQ GVVSTLVGSP SSPPPQPRKK KFKGKVD
//
