ID   A0A388LCK9_CHABU        Unreviewed;      1116 AA.
AC   A0A388LCK9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN   ORFNames=CBR_g30395 {ECO:0000313|EMBL:GBG80026.1};
OS   Chara braunii (Braun's stonewort).
OC   Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC   Chara.
OX   NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG80026.1, ECO:0000313|Proteomes:UP000265515};
RN   [1] {ECO:0000313|EMBL:GBG80026.1, ECO:0000313|Proteomes:UP000265515}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S276 {ECO:0000313|EMBL:GBG80026.1,
RC   ECO:0000313|Proteomes:UP000265515};
RX   PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA   Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA   Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA   Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA   Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA   Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA   Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA   Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA   Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA   Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA   Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA   Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA   Rensing S.A.;
RT   "The Chara Genome: Secondary Complexity and Implications for Plant
RT   Terrestrialization.";
RL   Cell 174:448-464(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GBG80026.1}.
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DR   EMBL; BFEA01000335; GBG80026.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A388LCK9; -.
DR   EnsemblPlants; GBG80026; GBG80026; CBR_g30395.
DR   Gramene; GBG80026; GBG80026; CBR_g30395.
DR   Proteomes; UP000265515; Unassembled WGS sequence.
DR   CDD; cd00303; retropepsin_like; 1.
DR   CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR   CDD; cd01647; RT_LTR; 1.
DR   Gene3D; 3.10.20.370; -; 1.
DR   Gene3D; 3.30.70.270; -; 2.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR000477; RT_dom.
DR   InterPro; IPR041577; RT_RNaseH_2.
DR   PANTHER; PTHR24559:SF437; RIBONUCLEASE H; 1.
DR   PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR   Pfam; PF17919; RT_RNaseH_2; 1.
DR   Pfam; PF08284; RVP_2; 1.
DR   Pfam; PF00078; RVT_1; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50878; RT_POL; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT   DOMAIN          678..857
FT                   /note="Reverse transcriptase"
FT                   /evidence="ECO:0000259|PROSITE:PS50878"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        144..158
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        159..174
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1116 AA;  126316 MW;  676AF6073B662632 CRC64;
     MKVEGQQPST STPPSPPLTA TQQEKKELQE QLRWQQDRLA ELERQEATEL EAATDNSRRD
     YLLQQLDKVL TDDRCAQVTK HLAETIILEH KITSFYFTNW DDRFERLERR VDDLAAQQSK
     ILDAIQNLTA QLSTAKLIAP QLPLLKPKPS PPSRPSTPPG SAHYSRSPSH SQKAAGKATY
     AAVTAGDQRG PKIPPPNKFR GDDPKTDVGD WAAGTKAYLR GFVCAEQTKA GTVLGLLEGP
     ALKWATSTSS SLQQSMEDWT FGLGVDRLLQ TLEDRFADKE RASKAADRIA RLGQQRYSGT
     LQTLFTEFKQ LTSTPGLVMS RDDLLTNFCR AAPEKFVVAL YSAGHKDWRS FGRAALDMEA
     KLHVQAPSSD RRKVSSVAPS STQVDESAAV SIETVGDNVC LGTARATSFC YEDPDPDQDP
     GQDELQSLAT FFLHLKEQKK RKSDLIMLRP LINRIRITGF LDCGATRNFI SPSAVKKLHL
     RMKVQQLQQP LLVRIDDSTV PSIREKVQGI PVTFDSAGEV RHSLNFYIFP ELPFDLVFSM
     QWLKAVNPRI DWQIPKVELP NSQGVYQPCM IAADHHLKTS CYCLRAREFH DLSRRYHHER
     LFIALVKQTH APPVSCPPEI QQVVDQYADL TKEPFGLPNW PTKHHIELLP GAVPPKGRIY
     KMFPAELEEP RKQLETLTSK GWIRRNTSEF GAPVLFMPKG NGEFRMCIDY RGLNKITGKS
     TEPLPRIDDL LDMVQGCTVF SKVDLKSGYH QIEMAEEDVY KIAFKTRYGI YEFLVMPFRL
     CNAPGTFQTE MYRIFRPYLD KFMVVYLDDI LVFSKTAREH VEHLALVLQS LRDSLYKINR
     EKSSFGVPSV IYLGHVISGD GPTPEAAKIA AIQEWPQPQT VRDVRSFMGL ASYYRKFVRN
     FSAVAASLTN LTKKDTPFLW SLPCQLAFIR LKKALTRAPM LKLPDPTLPF ILTTDASQYG
     IGAVLQQDDG NGLRPVEFMS KKIKTQKLQD STYEKELYAL VCALKHWKHF LLGRHFKIFS
     NHSTLQWMKS QGKLNDKLAR YIQFIDMFDF ELKHKKGCYN KVADALSRRP DSFAPISSTH
     SFGEETRQTI ARLLPQDETF GPIVRSLQAD PNSEPG
//