ID A0A388M357_CHABU Unreviewed; 1269 AA.
AC A0A388M357;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Reverse transcriptase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBR_g48591 {ECO:0000313|EMBL:GBG88981.1};
OS Chara braunii (Braun's stonewort).
OC Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC Chara.
OX NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG88981.1, ECO:0000313|Proteomes:UP000265515};
RN [1] {ECO:0000313|EMBL:GBG88981.1, ECO:0000313|Proteomes:UP000265515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S276 {ECO:0000313|EMBL:GBG88981.1,
RC ECO:0000313|Proteomes:UP000265515};
RX PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA Rensing S.A.;
RT "The Chara Genome: Secondary Complexity and Implications for Plant
RT Terrestrialization.";
RL Cell 174:448-464(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG88981.1}.
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DR EMBL; BFEA01000708; GBG88981.1; -; Genomic_DNA.
DR EnsemblPlants; GBG88981; GBG88981; CBR_g48591.
DR Gramene; GBG88981; GBG88981; CBR_g48591.
DR Proteomes; UP000265515; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 1.10.340.70; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR001584; Integrase_cat-core.
DR InterPro; IPR041588; Integrase_H2C2.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR24559:SF439; RNA-DIRECTED DNA POLYMERASE HOMOLOG; 1.
DR PANTHER; PTHR24559; TRANSPOSON TY3-I GAG-POL POLYPROTEIN; 1.
DR Pfam; PF13650; Asp_protease_2; 1.
DR Pfam; PF17921; Integrase_H2C2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50994; INTEGRASE; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT DOMAIN 518..697
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT DOMAIN 879..1039
FT /note="Integrase catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50994"
FT REGION 172..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1240..1269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1064..1091
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1269 AA; 144600 MW; 9A55B4B91A8C238C CRC64;
MATIHGVQVS DLHKKVTWED MAKEWKKRFI VDDAPALAIN RIFAMAQGST PTRDWLADWQ
KIVATLDLNL PFPHLRREFY NRSCAALSLA LGDREQYHTF AEIINKAREI IKTNSSAEGE
ATPPSTPSDS AALLASSCTS GEDANVASSR YSYEDYAVYL VPPLDQPLHV QQSTACTVSS
PSATDSAPSS QSITGDSTSW SRLDELDPLT FTDFQWMPVP STGRLSKPHC NVLMAQLRDY
LHTAVPAPLM DDGVEVVNLH EYIAKIEREF KTQRYDDIDT PLLYIRIENG EATCSALIDC
GASRNYISQD FMVHAGLGPR VRRKSQPTQV KLADGHTHKS IDRCIDAVPV YFAPHASEAV
FFDILDTKFD MILGMSWLRS EDHPVNFFNR TVHIRDRTGV LVPCTVPLPH PSIKCHVVSA
ASMRASIIRD DIEEMGVCFL HALPPRDASS TGSSSDPRIT ELLDAYSDVF EGLHGVVPDR
PIRHEIILED GAVPPRGCIY RMSEEELSVL RAQLDDLLEK GWIRPSSSPY GAPVLFVRKK
NKDLRLCIDY RKLNAQTIRN TGPLPRIDDL LKRLGGAQFF SELDLKSGYH QLEIRKEDRY
KTSFKTRYGY FEWLVMPFGL TNAPATFQAA MTTEFRHMLD RFVLIYLVDI LVYSRSLDEH
VEHLRTVLER LRQAKYKANR DKCEFAQQEL EYMGHYVTPQ GILSSTIGRW MYFIDQFDFT
PKHLPDLSNR AADALSRRPD LCVMTHHAFA FDEELQRHFI RAYQSDPDFG TLYAQLSSDH
PPASHYRIAD GYLLLHSRGK DLLCVPRDRC LRTRLLGEYH DSRLAGHFGV NRTIARLRQR
FRWPDLIIDV TRYCDSCEVC RRSKPRNRNP YGELHPMPIP REPGLSIAMD VTGPFPRDRL
RHDGILTVVD RLSKYARFLP CKYYSMAPEL ARLLHTGWIC GHGVPEDIVS DRDTRFMSAF
WIALMQESDT TMKPCSARHP QTDGQTERAD QTAQMMLCTL IRPDHKDWVD RLPDIEFAYN
TSVHPAIGVT PFELRHGGRK GRIFADLRLP RPADIDAACS PASVRNYRDL LTQARXNMQK
AQVRMQQQTN RRRVPCPIHA GDLVWVSTEE FALEQDVSRK LLPKWFGPWS VTAAAGDEPD
DPSFVLNIPK HLTVHPVFHT SKLATYTPTK SDDFSGRRSQ DPPFMDGHQE VDRVITNRKY
SSKPRQYRVT FKACDRDNTR WISGADLKAS APLIYAHYER QRLAKGPPRP APPTRTVVPP
SDRQLRPRR
//
