ID A0A388M3V7_CHABU Unreviewed; 1112 AA.
AC A0A388M3V7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Reverse transcriptase {ECO:0008006|Google:ProtNLM};
GN ORFNames=CBR_g48979 {ECO:0000313|EMBL:GBG89270.1};
OS Chara braunii (Braun's stonewort).
OC Eukaryota; Viridiplantae; Streptophyta; Charophyceae; Charales; Characeae;
OC Chara.
OX NCBI_TaxID=69332 {ECO:0000313|EMBL:GBG89270.1, ECO:0000313|Proteomes:UP000265515};
RN [1] {ECO:0000313|EMBL:GBG89270.1, ECO:0000313|Proteomes:UP000265515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S276 {ECO:0000313|EMBL:GBG89270.1,
RC ECO:0000313|Proteomes:UP000265515};
RX PubMed=30007417; DOI=10.1016/j.cell.2018.06.033;
RA Nishiyama T., Sakayama H., Vries J.D., Buschmann H., Saint-Marcoux D.,
RA Ullrich K.K., Haas F.B., Vanderstraeten L., Becker D., Lang D.,
RA Vosolsobe S., Rombauts S., Wilhelmsson P.K.I., Janitza P., Kern R.,
RA Heyl A., Rumpler F., Villalobos L.I.A.C., Clay J.M., Skokan R., Toyoda A.,
RA Suzuki Y., Kagoshima H., Schijlen E., Tajeshwar N., Catarino B.,
RA Hetherington A.J., Saltykova A., Bonnot C., Breuninger H., Symeonidi A.,
RA Radhakrishnan G.V., Van Nieuwerburgh F., Deforce D., Chang C., Karol K.G.,
RA Hedrich R., Ulvskov P., Glockner G., Delwiche C.F., Petrasek J.,
RA Van de Peer Y., Friml J., Beilby M., Dolan L., Kohara Y., Sugano S.,
RA Fujiyama A., Delaux P.-M., Quint M., TheiBen G., Hagemann M., Harholt J.,
RA Dunand C., Zachgo S., Langdale J., Maumus F., Straeten D.V.D., Gould S.B.,
RA Rensing S.A.;
RT "The Chara Genome: Secondary Complexity and Implications for Plant
RT Terrestrialization.";
RL Cell 174:448-464(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBG89270.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BFEA01000726; GBG89270.1; -; Genomic_DNA.
DR EnsemblPlants; GBG89270; GBG89270; CBR_g48979.
DR Gramene; GBG89270; GBG89270; CBR_g48979.
DR Proteomes; UP000265515; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR CDD; cd09274; RNase_HI_RT_Ty3; 1.
DR CDD; cd01647; RT_LTR; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR041577; RT_RNaseH_2.
DR PANTHER; PTHR33064; POL PROTEIN; 1.
DR PANTHER; PTHR33064:SF36; RT_RNASEH_2 DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF17919; RT_RNaseH_2; 1.
DR Pfam; PF08284; RVP_2; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF54160; Chromo domain-like; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265515}.
FT DOMAIN 583..642
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|Pfam:PF00078"
FT DOMAIN 708..804
FT /note="Reverse transcriptase/retrotransposon-derived
FT protein RNase H-like"
FT /evidence="ECO:0000259|Pfam:PF17919"
FT REGION 30..70
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 858..883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1091..1112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 104..128
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 864..883
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT UNSURE 399
FT /note="D or N"
FT /evidence="ECO:0000313|EMBL:GBG89270.1"
SQ SEQUENCE 1112 AA; 124760 MW; D1714EE82B35D1AE CRC64;
MVPVWHPRAS IQSAREIPLL PLVQQRSSSD AGLPIERQGQ TGKLSTAESD STTLSTPLEP
VSSRVTGLHS EAQAEVDSPL LLLSFEDYAA RLVSTLGTQA QGQGVCAVSS PSGNGDISSS
SGSSRDSARE FNIEALGPLT SEDFAWLPLP TTGRLPGPQC ATLSAHLHTY LSFYAPPTSP
TDDEVEVGDI LAYTTKVARE FRNQRNDDNN APLMYVRIQV GQASCSALLD SGASRNFMSL
SFMQKAGLGA QVRRKANPTA IKLADGKTQQ LLDRYIEAVP VYFAPHACEP VTFDILDXDF
DIILGMPWLA SADHTTNFHR RTLRVRDTFG AEVACTIPLL HPSIQCQVVT AKSFRATCAY
EQPEEIGLCF LRTVAVASSS PTDLSSDPRV VRLLDQFADI FESPTGVVPD RPISHEIILE
ASXVPPKGCI YRMSEEELEV LRAQLDDLLV KGWIRPSSSP YGAPVLFVRK KNKDLRVCID
YRKLNAQTVK NAGPLPXINN LLERLGGAKY FSKLDLKSGY HQISIQLNXV GFEIRISSNL
HPAERLLQDR VQDAVRAFRV GGHAFWPHQR PGDLPPAMTN EFRAMLDWFV LVYLDDILVY
SRSLEDHLGH LRRVLETLRL AKYKANRDKC EFVRQELKYL GHFVTPEGIS PLSDKIQAVQ
AWPEPRNVTD VRSFLGLAGY YQRFIKGYSK IAAHLNKLQC EDQPFEFGEE ARGSFFALKA
ALLSAEVLRI YHPLLPTRVT TDASGYGIGA VLEQHDGVDW HPVEYFSKKV PIVHSIDDAR
KKELLAFVHX LKRWRHFLLG RSQFRWVTDN NXLVFYKTQD TINSTIARWM AFIDQFDFFP
DHIPGKLNRF ADALSRRPDH CTRSTQPSRS TTTCGTVSSA ATRPTPSFVT EQMQKAQAAM
IESANKHRCE SSCQVGDRVW VKSSELGQRH GISRKLMPQY FGPWEVLDIV GTEPDGPSYV
IRIPGHRRTY SVFHASKLAP FKETDQFPSR RSMLPPTMDG EVDIDDIVDH RELPVSRPTG
RGRPPKPKLQ YRIRFRHDTD LKEDRWFTRE ELMQTAPQVV AHYKKSLQKG KRXXVKDXAF
QRXVEAKEEG MRGHCLYEPQ SAPSGEPVGR PK
//
