ID A0A388SFF1_9BURK Unreviewed; 922 AA.
AC A0A388SFF1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA_1 {ECO:0000313|EMBL:GBO93424.1};
GN ORFNames=MESMUL_07780 {ECO:0000313|EMBL:GBO93424.1};
OS Mesosutterella multiformis.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sutterellaceae; Mesosutterella.
OX NCBI_TaxID=2259133 {ECO:0000313|EMBL:GBO93424.1, ECO:0000313|Proteomes:UP000266091};
RN [1] {ECO:0000313|EMBL:GBO93424.1, ECO:0000313|Proteomes:UP000266091}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4NBBH2 {ECO:0000313|EMBL:GBO93424.1,
RC ECO:0000313|Proteomes:UP000266091};
RX PubMed=30394865; DOI=10.1099/ijsem.0.003096;
RA Sakamoto M., Ikeyama N., Kunihiro T., Iino T., Yuki M., Ohkuma M.;
RT "Mesosutterella multiformis gen. nov., sp. nov., a member of the family
RT Sutterellaceae and Sutterella megalosphaeroides sp. nov., isolated from
RT human faeces.";
RL Int. J. Syst. Evol. Microbiol. 68:3942-3950(2018).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBO93424.1}.
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DR EMBL; BGZJ01000001; GBO93424.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A388SFF1; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000266091; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000266091};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocase {ECO:0000256|ARBA:ARBA00022967};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 587..918
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 922 AA; 99928 MW; 208F2603A24C7DB9 CRC64;
MEKIIIRGAK THNLKNVNAE LPRNRLVVIT GPSGSGKSSL AFDTLYAEGQ RRYLEGLSPY
ARQFLNIRNK PDVDSIEGLS PAIAIDQKNR SDNPRSTVGS STEILDYLRL LYSRVGTPYC
PDHHLPLEAT PVSVIAERLL AWPEETPVIL LSPIPADRRA NPKQLLADLA RQGFLRVRIG
SDIVETEEAS PDALADLSLR ADIVVDRLKL RKSSRGRLTE SLDLASRLSG GRVSAMNHRT
REETAFSTNF SCPLCDFSLK KLEPGLFSPQ TARGRCPTCG GTGTVPAVSI ESIIHPELSL
RAGAIPNWGE NSPKHFALLE AAANRASVSL DTPWEELSGK DRQFMLQGDP DQPEFPGIES
LITEEAETLS KADREKLLGP LLKEKTCPDC KGEKLSREAR NVFLTSEGKL FSYPSLLRMP
ISELEPLLGS LELGETARAV ADRILPPILD RLRYLNSVGL AYLTLDRPVT TLSGGESQRI
RLACELSSGL SGVMYVLDEP STGLHPADNE KLLDSLKRLR DAGNSVIVVE HDEDTIRSAD
YLIDMGPGSG ESGGEVIASG SLKEILKDPK SVTGTYLSHP ETTVQRNRSR RIGKKLLIKG
ARGHNLKNVS ASIPVGCLTV VSGVSGSGKS SLINGTLYPA LAAKLYRASA SPLPVDAIEG
LEHLDKVICI DQQPLGRTSR SNPATYMGIF QGIREIFAGT ALALERGYGA DRFSFNVKGG
RCEACQGEGI LKIGLQFLPD MQVPCDVCGG TRYNQETLEV RYQGKNIAEI LDLSVDQAIP
VFANHPAILR KLEALEAVGL GYIRLGQSSQ TFSGGEAQRV KIAVELAKTD TGRTLYLLDE
PTSGLHFREI SQLIALLQKI CDAGNTVVVI EHDMNVVASA DWVIDMGPGG EDGGRILCEG
TPEDIAACPE SVTGRFLQKK IA
//
