ID A0A392RVI7_9FABA Unreviewed; 80 AA.
AC A0A392RVI7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=PHD finger protein ALFIN-LIKE {ECO:0000256|RuleBase:RU369089};
DE Flags: Fragment;
OS Trifolium medium.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; Hologalegina; IRL clade; Trifolieae; Trifolium.
OX NCBI_TaxID=97028 {ECO:0000313|EMBL:MCI40389.1, ECO:0000313|Proteomes:UP000265520};
RN [1] {ECO:0000313|EMBL:MCI40389.1, ECO:0000313|Proteomes:UP000265520}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 10/8 {ECO:0000313|Proteomes:UP000265520};
RC TISSUE=Leaf {ECO:0000313|EMBL:MCI40389.1};
RX PubMed=29922311; DOI=10.3389/fpls.2018.00724;
RA Dluhosova J., Istvanek J., Nedelnik J., Repkova J.;
RT "Red Clover (Trifolium pratense) and Zigzag Clover (T. medium) - A Picture
RT of Genomic Similarities and Differences.";
RL Front. Plant Sci. 9:724-724(2018).
CC -!- FUNCTION: Histone-binding component that specifically recognizes H3
CC tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription
CC start sites of virtually all active genes.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SUBUNIT: Interacts with H3K4me3 and to a lesser extent with H3K4me2.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369089}.
CC -!- DOMAIN: The PHD-type zinc finger mediates the binding to H3K4me3.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- SIMILARITY: Belongs to the Alfin family.
CC {ECO:0000256|RuleBase:RU369089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:MCI40389.1}.
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DR EMBL; LXQA010279194; MCI40389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A392RVI7; -.
DR Proteomes; UP000265520; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR InterPro; IPR045104; Alfin.
DR InterPro; IPR021998; Alfin_N.
DR PANTHER; PTHR12321; CPG BINDING PROTEIN; 1.
DR PANTHER; PTHR12321:SF98; PHD FINGER PROTEIN ALFIN-LIKE 4; 1.
DR Pfam; PF12165; Alfin; 1.
PE 3: Inferred from homology;
KW Chromatin regulator {ECO:0000256|RuleBase:RU369089};
KW Metal-binding {ECO:0000256|RuleBase:RU369089};
KW Nucleus {ECO:0000256|RuleBase:RU369089};
KW Reference proteome {ECO:0000313|Proteomes:UP000265520};
KW Transcription {ECO:0000256|RuleBase:RU369089};
KW Transcription regulation {ECO:0000256|RuleBase:RU369089};
KW Zinc {ECO:0000256|RuleBase:RU369089};
KW Zinc-finger {ECO:0000256|RuleBase:RU369089}.
FT DOMAIN 1..78
FT /note="Alfin N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12165"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:MCI40389.1"
SQ SEQUENCE 80 AA; 9196 MW; C77A7C7D3C80680B CRC64;
KENLCLYGFP NEEWKVDLPA EEIPPELPEP SLGINFARPG MRKTDWLSLV AAHSDSWLCG
VAFYYGGEFG FNKSDRYFMF
//
