ID A0A395GK03_9EURO Unreviewed; 941 AA.
AC A0A395GK03;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DUF300-domain-containing protein {ECO:0000313|EMBL:RAK95821.1};
GN ORFNames=BO80DRAFT_439068 {ECO:0000313|EMBL:RAK95821.1};
OS Aspergillus ibericus CBS 121593.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1448316 {ECO:0000313|EMBL:RAK95821.1, ECO:0000313|Proteomes:UP000249402};
RN [1] {ECO:0000313|EMBL:RAK95821.1, ECO:0000313|Proteomes:UP000249402}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 121593 {ECO:0000313|EMBL:RAK95821.1,
RC ECO:0000313|Proteomes:UP000249402};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ824484; RAK95821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395GK03; -.
DR STRING; 1448316.A0A395GK03; -.
DR VEuPathDB; FungiDB:BO80DRAFT_439068; -.
DR OrthoDB; 2291142at2759; -.
DR Proteomes; UP000249402; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR CDD; cd12148; fungal_TF_MHR; 1.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR InterPro; IPR005178; Ostalpha/TMEM184C.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR InterPro; IPR001138; Zn2Cys6_DnaBD.
DR PANTHER; PTHR31001; UNCHARACTERIZED TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR PANTHER; PTHR31001:SF50; ZN(II)2CYS6 TRANSCRIPTION FACTOR (EUROFUNG); 1.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF03619; Solute_trans_a; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SMART; SM01417; Solute_trans_a; 1.
DR SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000249402};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 44..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 359..388
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000259|PROSITE:PS50048"
FT REGION 334..357
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 422..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 941 AA; 105919 MW; BF1ECFE060A297C4 CRC64;
MIISGASTVL ACLIIFALMM RHATRFSNPT EQIRVMRISS VVPVYSIFSF LSVCFPNGYV
YFSSWPDPFE GVALYSFFLL LCEFIAPSDE QRLQLIATQQ IKPSRLRRRR RSPPMDGLTW
FRRTYYVVVQ YPAVALITTV VACITQGAGK YCLESKEPYF AHIWITIIKN VSISFAVMAV
VKFYAQLKKD MEGHRALAKL LAFKLIVGLT FVESILFTIL RTASILKASS VMTYTDITIG
LPTMIICIQM VPLACFFHFA YSVTPYSVMK LPLANEPRYK PVDEIEEIKV RQKYQGGPLG
IYAWAMFFNP VAMAREFVFP LTLMRAAARS PEHQVLTPKQ LDERQSPAAA PPPPLNPRSC
IPCNRRKVRC DRHFPCGRCV KGAEECIFPG PKRAPRQLKR PPIAEVLAQL RLLEEEVQKL
RSQPLPPTAD PGSASGSSPL GIPAGQGPVG PSPQEGRLVV KEGLQFVSAV GGNWRDHSLR
DTFLQPARIQ SLWRVYQDNV APLIAVLHRP SVDVMIRQEL DNINPDPARE ALILAVCFAA
IVTLQPEQCR QLLGLDYDQA IQSYIHAVDQ ALVRANFIKT QNICVLQAAV VFLLTLRYRS
DSRLVWAASA VVVRVAQGQG VHRDGEVLGL SPFDAEMRRR LWWNICILDM ISSEDQGTDT
QVHPGMFDTR LPSNINGEDL SPSMTELPPE KVGATDITLA IVQCEIISQL YWPNGSHDPK
SPSKDSRESR VMKLASRIQN HYLEHLNLGV PIEWVYATII RLTVSKLWVS VHYKDLWNPA
TGTESELEVS QRACDEAFAV AVEAVEFTIL LQTNETTSQW SWLCKSYKQW HAVAFILAEL
CTRPITPATN RAWEMVNEIH RQWEEDDSQT SVMLRKPLRR LMERTAFARK ARLEPSPLRG
PPNSVIDPDV PGIGPDVVVN SDLYSLYSSG FGESELWIRE P
//
