ID A0A395I2I6_ASPHC Unreviewed; 309 AA.
AC A0A395I2I6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=catechol O-methyltransferase {ECO:0000256|ARBA:ARBA00012880};
DE EC=2.1.1.6 {ECO:0000256|ARBA:ARBA00012880};
GN ORFNames=BO97DRAFT_442042 {ECO:0000313|EMBL:RAL14157.1};
OS Aspergillus homomorphus (strain CBS 101889).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1450537 {ECO:0000313|EMBL:RAL14157.1, ECO:0000313|Proteomes:UP000248961};
RN [1] {ECO:0000313|EMBL:RAL14157.1, ECO:0000313|Proteomes:UP000248961}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101889 {ECO:0000313|EMBL:RAL14157.1,
RC ECO:0000313|Proteomes:UP000248961};
RG DOE Joint Genome Institute;
RA Vesth T.C., Nybo J., Theobald S., Brandl J., Frisvad J.C., Nielsen K.F.,
RA Lyhne E.K., Kogle M.E., Kuo A., Riley R., Clum A., Nolan M., Lipzen A.,
RA Salamov A., Henrissat B., Wiebenga A., De vries R.P., Grigoriev I.V.,
RA Mortensen U.H., Andersen M.R., Baker S.E.;
RT "The genomes of Aspergillus section Nigri reveals drivers in fungal
RT speciation.";
RL Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. Cation-dependent O-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00023453}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KZ824276; RAL14157.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395I2I6; -.
DR STRING; 1450537.A0A395I2I6; -.
DR VEuPathDB; FungiDB:BO97DRAFT_442042; -.
DR OrthoDB; 4040098at2759; -.
DR Proteomes; UP000248961; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006584; P:catecholamine metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR002935; SAM_O-MeTrfase.
DR PANTHER; PTHR43836; CATECHOL O-METHYLTRANSFERASE 1-RELATED; 1.
DR PANTHER; PTHR43836:SF2; CATECHOL O-METHYLTRANSFERASE 1-RELATED; 1.
DR Pfam; PF13578; Methyltransf_24; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51682; SAM_OMT_I; 1.
PE 3: Inferred from homology;
KW Catecholamine metabolism {ECO:0000256|ARBA:ARBA00022939};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:RAL14157.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000248961};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:RAL14157.1}.
FT REGION 278..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 309 AA; 34647 MW; 65D62C45963549DC CRC64;
MPDTEEPPMF TKYPSLRKMA ALEESEIVES HDGREITLLK HIYAHPELDT KLRGSPVAIL
EVMDEFAAQE DFLINIGPDK AGKLAVLVRE HRPRVVVELG GYVGYSAILF GSILKEIWTQ
NHPNNADLEG EDDHSKDQPR LYSIEIDPLV ASIAMNLVSL AGLQGFVEVV VGASAHTLRR
MHEQGTFSDR GIDLLFMDHD EALYAADIQV AEELGLLKTD GALVIADNVM RPGAPAYRDY
MRKNPRLRQS WGLPGLIVPG DLADEMEISV VGRKMLSEKK PSRAMEKVEE ENWVDEQKQP
DRKRKEVTN
//
