ID   A0A395JPM9_9GAMM        Unreviewed;      1060 AA.
AC   A0A395JPM9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Multidrug efflux pump subunit AcrB {ECO:0000313|EMBL:RBP50660.1};
GN   ORFNames=DFR28_10271 {ECO:0000313|EMBL:RBP50660.1};
OS   Arenicella xantha.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Arenicellales;
OC   Arenicellaceae; Arenicella.
OX   NCBI_TaxID=644221 {ECO:0000313|EMBL:RBP50660.1, ECO:0000313|Proteomes:UP000253083};
RN   [1] {ECO:0000313|EMBL:RBP50660.1, ECO:0000313|Proteomes:UP000253083}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 24032 {ECO:0000313|EMBL:RBP50660.1,
RC   ECO:0000313|Proteomes:UP000253083};
RA   Goeker M.;
RT   "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT   most valuable type-strain genomes for metagenomic binning, comparative
RT   biology and taxonomic classification.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RBP50660.1}.
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DR   EMBL; QNRT01000002; RBP50660.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A395JPM9; -.
DR   InParanoid; A0A395JPM9; -.
DR   OrthoDB; 5287122at2; -.
DR   Proteomes; UP000253083; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF33; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000253083};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        331..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        358..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        460..479
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        530..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        881..901
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        908..928
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        934..959
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        980..999
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1011..1037
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1060 AA;  115304 MW;  A66C6B12AAC06485 CRC64;
     MNGIIEWFAR HPVASNLLMG FMLIGGLISM SNTSQEAFPE FTLEIIQVEV PYVGASPDEI
     EKSIIQPLEQ QLNGVEGVKE VTATAAEGVG VVKLEFSRTA DIGRALNDVK SEVDRITVFP
     DDAEEPIVSQ VSGKTRVAEI AISGALPEAA LKELAYRIKD DLVLEDNISL IEVKRARDYE
     ISIEVSRDNL RAYDVSLADL SNAIRLESLE LPGGDIDTAK ENILIRTVGR NLTRQDFEEI
     IVRSSPSDGV IRVRDIARVV DGFQERDQFA LFNGQPAVFL DVFRVGDERV LDVIESAETY
     IEQSLKPSLP ESVNVVIWRN DAVELDQRID LLVKNAIIGI LLVALALTLF LDLRLAFWVS
     AGIGVSFTAA FIPMSLLGLS INSLSMFGFI LAIGIVVDDA IVTGENIFAE AERGTPPMEA
     AVKGASRVAA PVIFAVSTTV AAFVPLLLLP GILGKFLTDI PAVVIIILGL SLIESLLILP
     HHLSHINVQE PPRNFVFQFF AKARDKVDGA LKRFIEGPLE RILDFTTKHW FVTITGAVTV
     LVLTIGILAN GYIKFSFFPQ IEGNYVTASV EMTEGTSLQR TAQLIAEVEQ AGVEVARSMA
     TDKQTVDELM LGQLVLVGTQ EEAGGPPGSG GLNAPKSNQG SVVIQLASPE DRDFSSSEFE
     AKWRKALAPF KSQAKISVAS NLVSLGASVQ VEVSADTDSS LREAISQTEA GLNSINGVFD
     VRNDFDAGKR EFKIELKDEA RRYGLSLQSL ALQVRGAFFG DEALRVQRGR DEVRVYVRLP
     KTERSHISDL FDYRIQTSTG EFIPLSQVAN VTETLSPSTI NRRNGRRLIT ITADVDNAVI
     SGQQANAVLT EAILPEIEKS VPDVRFDFGG EAREMGDVGS VLGRNFTLAL LAIFILLAIP
     FRSYSQPIVV MLAIPFGLVG AVLGHLVMDL YMGLLSIFGI VGLAGVVING ALVQVDFANE
     LRAQGVDSRQ AWIEAGKSRF RPIFLTALTT FLGVGPLMLE QSVQAQFLIP MAASIAFGVL
     IGTFIQMLLV PALGSMLDRL TIAREQRRTR SNETELQGQV
//