ID A0A395LMI2_9SPHN Unreviewed; 699 AA.
AC A0A395LMI2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:RDS77965.1};
GN Name=mrdA {ECO:0000313|EMBL:RDS77965.1};
GN ORFNames=DL238_10380 {ECO:0000313|EMBL:RDS77965.1};
OS Alteriqipengyuania lutimaris.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Alteriqipengyuania.
OX NCBI_TaxID=1538146 {ECO:0000313|EMBL:RDS77965.1, ECO:0000313|Proteomes:UP000254101};
RN [1] {ECO:0000313|EMBL:RDS77965.1, ECO:0000313|Proteomes:UP000254101}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S-5 {ECO:0000313|EMBL:RDS77965.1,
RC ECO:0000313|Proteomes:UP000254101};
RA Chen X., Liu J.;
RT "Erythrobacter nanhaiensis sp. nov., a novel member of the genus
RT Erythrobacter isolated from the South China Sea.";
RL Submitted (JUL-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RDS77965.1}.
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DR EMBL; QRBB01000001; RDS77965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395LMI2; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000254101; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 66..237
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 270..588
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 652..699
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..678
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 77390 MW; 75631FE91D418E64 CRC64;
MPFGLTKQVL NESTLTNSFD RRSFVLGIGG LSVGILLAGR MGYLAIAEND KYAVESESNR
VNLTLIPPRR GWIVDRNGAP LASNQADFRV DIIPERLQDG ERELEALGKL LDLDDAKMRD
LRKKIDESAG YAPIEVASGL DYDAFAAVSI RLPELPGVVP QRGFSRYYPT GPSVGHLLGY
VGAASREEFE EDRNPILITP GYKIGKDGLE KQFEQRLRGT PGARRVEVTA SGRIVRDLST
RPDVQGDPIQ LTIDGPLQDY AARRIGLESG SVVVMDCLTG DLMCMASMPS FDPNSFSDGI
GSVEYAMLSE NERVPLRNKV LKGLYPPGST VKPMHAMAFM HEGIDPNEAI MCGGGRRIGN
RFFNCWSNHG RVDMAKGIYQ SCDSYFYHFA QQVGFDKVAA YARRFGLGQE FDLPVASQFY
GTVPDPAWKL EKYDQEWQPY DTVNASIGQG YYLTSPLQLA VMATRLATGR IVTPSLIKTN
ERKRFASLDF NKDQIDYIHQ AMSDVVNGPG TAGRARLPID DILMAGKTGT AQVVSLSVSD
GRSGPWKYRD HGLFVFYAPF DNPRYAGAVV IEHGGGSSAA YPIARDVMTF LFDPQKAMDA
LRTFEEQWGG TAQQRLQRRY QEYARAAGET IPPTAPLDRE IQERVDAEAR IEAQRREAFA
RENPRRRPRN DLDETNQRDR GAQAGVPGRA QGRAQGDAQ
//
