ID   A0A395M568_9HYPO        Unreviewed;       951 AA.
AC   A0A395M568;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Reverse transcriptase {ECO:0000313|EMBL:RFN42720.1};
DE   Flags: Fragment;
GN   ORFNames=FIE12Z_12733 {ECO:0000313|EMBL:RFN42720.1};
OS   Fusarium flagelliforme.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium incarnatum-equiseti species complex.
OX   NCBI_TaxID=2675880 {ECO:0000313|EMBL:RFN42720.1, ECO:0000313|Proteomes:UP000265631};
RN   [1] {ECO:0000313|EMBL:RFN42720.1, ECO:0000313|Proteomes:UP000265631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 13405 {ECO:0000313|EMBL:RFN42720.1,
RC   ECO:0000313|Proteomes:UP000265631};
RX   PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA   Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA   Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA   Busman M., Gutierrez S.;
RT   "Evolution of structural diversity of trichothecenes, a family of toxins
RT   produced by plant pathogenic and entomopathogenic fungi.";
RL   PLoS Pathog. 14:e1006946-e1006946(2018).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFN42720.1}.
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DR   EMBL; PXXK01000691; RFN42720.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A395M568; -.
DR   STRING; 2594813.A0A395M568; -.
DR   Proteomes; UP000265631; Unassembled WGS sequence.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   PANTHER; PTHR33481; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR33481:SF1; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF14529; Exo_endo_phos_2; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleotidyltransferase {ECO:0000313|EMBL:RFN42720.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265631};
KW   RNA-directed DNA polymerase {ECO:0000313|EMBL:RFN42720.1};
KW   Transferase {ECO:0000313|EMBL:RFN42720.1}.
FT   DOMAIN          531..656
FT                   /note="Endonuclease/exonuclease/phosphatase"
FT                   /evidence="ECO:0000259|Pfam:PF14529"
FT   REGION          1..85
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          88..161
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        28..69
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..85
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         951
FT                   /evidence="ECO:0000313|EMBL:RFN42720.1"
SQ   SEQUENCE   951 AA;  107855 MW;  22026DC4FFD3CE0C CRC64;
     MADPMGAEIV VEQDAPFSTP KRPSRVVKPT SKVRDTARQL EDTAIETRRN TRHTTRNVPA
     EEQIDRPTEA RKNNGSGSSS GSDGRAMLQK ALDLLAESRR ETKRLQEALK EQMEMTKELQ
     EAVAKQEETM HEMAKQMVEM KERMTEELQR AREQLETIAT NATDGPHRSY ADVTRLTPFL
     PHNDSRTVTA PLNPTDVFYC TIDVSRLEED EARLSAGTIR ATVENQVRSE LDNPTWRCRA
     VTKDPKNPHR VRITCRDESE HEIVKRVAET KLAPGARILR DDLYPIRVDN VSRIAVLNER
     NEVRAEITEM LGRENDTEVA KIAWLSKRDV PKAYGSMVVY LKKRSEARRF INEGFFVAGG
     ESGTTKVFER RDRPKQYHKS AADARKNVIT TAHAQERFRN VSHAAAPTSH IAETVGSSIH
     YNMNSIFRLF QLNVRKQGPV HDRLMNDKDI QDATVLAIQE PQARRIQGRL LTTPMGHYKW
     IKMVPTTERE GRWVIRSMLW VKKEVEAEQV PIDSPDVTAA VVRLPDRLVF TASVYVPGGD
     AQALQDICAK LRKAIGEVRR RSGRAVDVVV VGDFNRHDQM WGGDDVSGER QGEADPIIDL
     MNDFMLRSIL RRGTKTWQSG DYETTIDLVL ASEELANAAI KCAIHGTEHG SDHRTIETVF
     DISVPAPKQE ERLLFKNAPW KDINSRITGT LRSRPVGNTV QQKTDRLMSA VLDAVQVLTP
     KAKPSPYAKR WWTNDLTQLR HVYTYWRNRA RAARRAGQNT ADLEDTAKAA AKQYHDATRQ
     RKNTHWKEFL ADNDNIWKAA KYIKSGDDAA FGKVPQLVKA DGTATTSHKE QAEELLAKFF
     PPLPDDIEDE GPKQQRNPVT MPNLTLEEVE RQLWATKSWK APGEDGLPAI VWKQVWPSVK
     HDVLAIFQAS LEEGVIPKQW RHARIIPLKK PGKDDYTVAK AWRPISLLAT L
//