ID A0A395M921_9HYPO Unreviewed; 489 AA.
AC A0A395M921;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=FIE12Z_11981 {ECO:0000313|EMBL:RFN43773.1};
OS Fusarium flagelliforme.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium incarnatum-equiseti species complex.
OX NCBI_TaxID=2675880 {ECO:0000313|EMBL:RFN43773.1, ECO:0000313|Proteomes:UP000265631};
RN [1] {ECO:0000313|EMBL:RFN43773.1, ECO:0000313|Proteomes:UP000265631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13405 {ECO:0000313|EMBL:RFN43773.1,
RC ECO:0000313|Proteomes:UP000265631};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFN43773.1}.
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DR EMBL; PXXK01000507; RFN43773.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395M921; -.
DR STRING; 2594813.A0A395M921; -.
DR OrthoDB; 1743223at2759; -.
DR Proteomes; UP000265631; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF423; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000265631};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 21..489
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5017101662"
FT DOMAIN 29..343
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 331..355
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 53837 MW; FBE1A0723FB37035 CRC64;
MQIGVFNVVA VLSGLAVVFA NDICTAPSLT VKTDQGEVKG FRDESSNVAQ FLGIPYGEQL
RWSPAIPKGK FGKLNATSFG PNCPQSEPAA TGPWAPEFLI KPNSTSENCL FLNVWAPSHA
LCPETEPLPV IVWIHGGGFV EGGGGIAYQI PKKWVERSQK HIVVSINYRL GVFGFPNAPS
LGPKQQNLGL LDQRLAMQWV NDNISRFGGD PKRIILWGQS AGAMSVAFYQ YAYPKTPIAA
GYIENSGSAF LGLRNRDDTN SNFTSLARSF GCRRDYVECL RRVPWKDVQR HVDEAKTMSF
VPVVDERTVF SNYTERILNV TKLPAIIGST RDEGDLTAKP EHTGANTPDQ VKPDDTFHCP
AHYETIVRSS AGVNTWRYMY SPNFTNIMPG GEGAFHSAEL PLIMGTHDEA REKSSEFEYE
VSHAMQDCWL AFAQDPSAGL TRMGWEPTPK RGVQSGIEFG FKNEIVVRPY SWSSLEKGCN
KAAAVKNSA
//
