ID   A0A395MDI9_9HYPO        Unreviewed;       868 AA.
AC   A0A395MDI9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=MI domain-containing protein {ECO:0000259|PROSITE:PS51366};
GN   ORFNames=FIE12Z_9895 {ECO:0000313|EMBL:RFN45906.1};
OS   Fusarium flagelliforme.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium incarnatum-equiseti species complex.
OX   NCBI_TaxID=2675880 {ECO:0000313|EMBL:RFN45906.1, ECO:0000313|Proteomes:UP000265631};
RN   [1] {ECO:0000313|EMBL:RFN45906.1, ECO:0000313|Proteomes:UP000265631}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 13405 {ECO:0000313|EMBL:RFN45906.1,
RC   ECO:0000313|Proteomes:UP000265631};
RX   PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA   Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA   Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA   Busman M., Gutierrez S.;
RT   "Evolution of structural diversity of trichothecenes, a family of toxins
RT   produced by plant pathogenic and entomopathogenic fungi.";
RL   PLoS Pathog. 14:e1006946-e1006946(2018).
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000256|ARBA:ARBA00004604}.
CC   -!- SIMILARITY: Belongs to the CWC22 family.
CC       {ECO:0000256|ARBA:ARBA00006856}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RFN45906.1}.
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DR   EMBL; PXXK01000334; RFN45906.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A395MDI9; -.
DR   STRING; 2594813.A0A395MDI9; -.
DR   Proteomes; UP000265631; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   Gene3D; 1.25.40.180; -; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR003891; Initiation_fac_eIF4g_MI.
DR   InterPro; IPR003890; MIF4G-like_typ-3.
DR   PANTHER; PTHR18034; CELL CYCLE CONTROL PROTEIN CWF22-RELATED; 1.
DR   PANTHER; PTHR18034:SF4; NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF02854; MIF4G; 1.
DR   SMART; SM00543; MIF4G; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS51366; MI; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000265631}.
FT   DOMAIN          642..776
FT                   /note="MI"
FT                   /evidence="ECO:0000259|PROSITE:PS51366"
FT   REGION          1..309
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..140
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..189
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..248
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..284
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   868 AA;  97926 MW;  65712E19F3D2BC4E CRC64;
     MASTLELQQK LYKRMGLDVP EPKPQRNGRP KSSHQLSRKE QRKAQRVQKK SHVYTRPTQQ
     RPQPTHHTQK KPTGPQRKPQ NNKPQPKSKQ VSEDEDDEDD EDEDLGDMSL DEDEDEDEDE
     DEDLDDSMDE DEEDEDDESE TETKSQNKNA KKGVSKAVQE RLNQDDAEIE AFERKLGIKK
     GRKSLPQSFK EDGLGDLLGD LSGEEDLSDN DNDNKKRKSE YDEWLASKRR KTAEPPSRAK
     GLKGDDLDMN EDSGDEDDDL DLMDEDDDDG GDFDDGESFG GFDDDDAGDD RPAEPRQREN
     PYVAPTSGVA VAKYVPPSLR RAASSDDERK SRLRKQVQGL INRLTDANIL SIVKSVEELY
     QNNARGDVSD IITDAIMAQI SKPETLPDQF FVLTGGFAAA TYRLVGSSFG TVLIRRIVED
     FKGHYEQASK ELSAESAIQK EASNILTLLT QLYVFEVVTC KIIFDYMEKL LSDLNEINVE
     LLLRICRMAG RMLKQDDERT LKHVAGVLNQ SVAKAGFNNI SARTKFIVET ITDLTKGKRK
     AKGLDFTVVS EHVQRMKKRL VELKSQARRL NGLSPLAVGL VDIEEAETRG QWWLPSASVP
     STLMDKSKKG RTSDTEMSDH EDMDIVLPDY PKKARAQGLN GTAQIAIFTA LMTASNFEHA
     YRQFVNLKLK KDDQLALATV LVQCAGSEMQ YNPYYALVGG KACMLNSRIR FAIQDRLWKI
     FRSLGESMFG EAPEEDETAD AERMKDERRI TNVAKFYADL VADGTLNIAI LKPLELPETN
     HWASTFVQLF IIALMKECRS KKKEPEEDIK LEKIFGAARD LPGLAAGIHW MLRKKIRKTK
     LISAKELKKL EGVIEKAQII VRPTAIEI
//