ID A0A395MGB8_9HYPO Unreviewed; 613 AA.
AC A0A395MGB8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Glucose repression regulatory protein tup1 {ECO:0000313|EMBL:RFN46810.1};
GN ORFNames=FIE12Z_8938 {ECO:0000313|EMBL:RFN46810.1};
OS Fusarium flagelliforme.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium incarnatum-equiseti species complex.
OX NCBI_TaxID=2675880 {ECO:0000313|EMBL:RFN46810.1, ECO:0000313|Proteomes:UP000265631};
RN [1] {ECO:0000313|EMBL:RFN46810.1, ECO:0000313|Proteomes:UP000265631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13405 {ECO:0000313|EMBL:RFN46810.1,
RC ECO:0000313|Proteomes:UP000265631};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFN46810.1}.
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DR EMBL; PXXK01000283; RFN46810.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395MGB8; -.
DR STRING; 2594813.A0A395MGB8; -.
DR Proteomes; UP000265631; Unassembled WGS sequence.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.5.340; -; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR013890; Tscrpt_rep_Tup1_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22847:SF748; TRANSCRIPTIONAL REPRESSOR TUP11; 1.
DR PANTHER; PTHR22847; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08581; Tup_N; 1.
DR Pfam; PF00400; WD40; 7.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 4.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000265631};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 11..78
FT /note="Transcriptional repressor Tup1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08581"
FT REPEAT 360..394
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 395..436
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 443..477
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 481..522
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 534..575
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 576..613
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 81..266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 123..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 66149 MW; A1D55B4FB447573A CRC64;
MGAGPQGNST RLNELLEQIR VEFETQMRAT ENYEHQIAAQ VSEMQMVREK VYQMEQTHLG
LKQKYEDEIS ALRHQLDAAR KGGLQGGMPG PPQHAAPSQQ PPSIAPGNGL FSGIMAGGSQ
GGLAPPQQGQ QQSQQGQPQG AQQPQQSQQG HAPPQEQPLG PQHQMSQGPP GLPVPPHPNA
QQAPYSQNYP PGPVSNGMGP QPQSTASPGP GRRGIGRPPG AVGGPATPQI NTPVPYPGSA
ASPQVSHPTP DHPRMAGPHA SAVGNSLGDL EVDNVAPHNK KTGNDWYAIF NPQVQRVLDV
DLVHSLNHES VVCCVRFSHD GKYVATGCNR SAQIFDVQTG EKVCVLEDHN ASDMSADLYI
RSVCFSPDGR YLATGAEDKL IRVWDIQTRT IRNHFSGHEQ DIYSLDFARD GRTIASGSGD
RTVRLWDIEQ GTNTLTLTIE DGVTTVAISP DTQFVAAGSL DKSVRVWDIH SGFLVERLEG
PDGHKDSVYS VAFSPSGKDL VSGSLDRTIK MWELSTPRQG NQPGPKGGKC VKTFEGHRDF
VLSVALTPDT NWVLSGSKDR GVQFWDPRTG TTQLMLQGHK NSVISVAPSP QGRYFATGSG
DMKARIWSYR PFS
//
