ID A0A395MGZ3_9HYPO Unreviewed; 365 AA.
AC A0A395MGZ3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 22-FEB-2023, entry version 16.
DE SubName: Full=Putative phosphopantothenate-cysteine ligase {ECO:0000313|EMBL:RFN47172.1};
GN ORFNames=FIE12Z_8585 {ECO:0000313|EMBL:RFN47172.1};
OS Fusarium flagelliforme.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC Fusarium incarnatum-equiseti species complex.
OX NCBI_TaxID=2675880 {ECO:0000313|EMBL:RFN47172.1, ECO:0000313|Proteomes:UP000265631};
RN [1] {ECO:0000313|EMBL:RFN47172.1, ECO:0000313|Proteomes:UP000265631}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13405 {ECO:0000313|EMBL:RFN47172.1,
RC ECO:0000313|Proteomes:UP000265631};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the PPC synthetase family.
CC {ECO:0000256|ARBA:ARBA00005703}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFN47172.1}.
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DR EMBL; PXXK01000269; RFN47172.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395MGZ3; -.
DR STRING; 2594813.A0A395MGZ3; -.
DR OrthoDB; 6287at2759; -.
DR Proteomes; UP000265631; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.10300; CoaB-like; 1.
DR InterPro; IPR035929; CoaB-like_sf.
DR InterPro; IPR007085; DNA/pantothenate-metab_flavo_C.
DR PANTHER; PTHR12290; CORNICHON-RELATED; 1.
DR PANTHER; PTHR12290:SF2; PHOSPHOPANTOTHENATE--CYSTEINE LIGASE; 1.
DR Pfam; PF04127; DFP; 1.
DR SUPFAM; SSF102645; CoaB-like; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:RFN47172.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265631}.
FT DOMAIN 48..102
FT /note="DNA/pantothenate metabolism flavoprotein C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04127"
FT REGION 205..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..222
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 365 AA; 40960 MW; 86E673A8E55FBEF5 CRC64;
MAAPANTTAE ALASEEAYFS QNPPPRNLSA HTALAAGFIS SHAAAGRRVV LVTSGGTTVP
LEKQTVRYID NFSAGTRGAT SAEYFLEAGY AVIFLHRQFS LLPYSRHYSH ATDCFLDFLT
EDADDRIAVR GEVQDKMREV LRKYRKARDD NMLLTLPFVT IVDYLHELRE IARLMRPLGP
SGLLYLAAAV SDFFVPPNRM AEHKIQSTNA VEQKRPEDEE TFDNFDSSPS VPRSKRLIVD
LDPVPKFLKN LVDGWAPEGM IVSFKLETDP ALLVRKARYS LDRYQHHLVI GNLLSTRKWE
VVFVSPGRDD RWVRVPREGG WGEAEGRPLV AEELPAQDPD VEIESLIIPA VQELHGEHIK
GQNKK
//
