ID A0A395NTB6_TRIAR Unreviewed; 424 AA.
AC A0A395NTB6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 11.
DE SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:RFU79067.1};
GN ORFNames=TARUN_3196 {ECO:0000313|EMBL:RFU79067.1};
OS Trichoderma arundinaceum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=490622 {ECO:0000313|EMBL:RFU79067.1, ECO:0000313|Proteomes:UP000266272};
RN [1] {ECO:0000313|EMBL:RFU79067.1, ECO:0000313|Proteomes:UP000266272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 40837 {ECO:0000313|EMBL:RFU79067.1,
RC ECO:0000313|Proteomes:UP000266272};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00038048}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFU79067.1}.
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DR EMBL; PXOA01000178; RFU79067.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395NTB6; -.
DR Proteomes; UP000266272; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR005097; Sacchrp_dh_NADP.
DR PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266272};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 294..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..143
FT /note="Saccharopine dehydrogenase NADP binding"
FT /evidence="ECO:0000259|Pfam:PF03435"
SQ SEQUENCE 424 AA; 47265 MW; D51DFB30746AAAF5 CRC64;
MPFKEHNRQY DLVVFGATGH TGRMAAEYIT IHFPVNVKWA VAGRSESKLQ AIVEDCKKLH
SDRSPPAIET ANIKSQEEID ALAKKTFVMI QLVGPYSLHS GEHVVKACAE AGTHYFDATG
ESPWVYKMMK KYGKAAKESG AILIPQMALE SAPADLCTWA LASVLRKQMD AKTKDVVISI
HNMRTVPSGG TLSTVLNLHE CVTPSEFAEA EKPFAHSPVP YPGGDRGHKI SIWQKIFGVH
HVPNLGTLTS AFTYDADRPV IERSWGLLSE IPSRKDEFYG PNFHWEEYHR ARNWLYGVAI
HWIIVVCGFL LSFGASFRVL AEKVVPAPGT GPSREEMDKD EAEWRGIANP DTELPSNKQA
FCRAWYYGSM YMMSALFCCE GARTVLEDDL ELDGGFYTPC CLGQGLIDRA HDGGFKMETR
LQDK
//
