ID A0A395NY57_TRIAR Unreviewed; 509 AA.
AC A0A395NY57;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Translation initiation factor eif-2b subunit family {ECO:0000313|EMBL:RFU81032.1};
GN ORFNames=TARUN_1125 {ECO:0000313|EMBL:RFU81032.1};
OS Trichoderma arundinaceum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Hypocreaceae; Trichoderma.
OX NCBI_TaxID=490622 {ECO:0000313|EMBL:RFU81032.1, ECO:0000313|Proteomes:UP000266272};
RN [1] {ECO:0000313|EMBL:RFU81032.1, ECO:0000313|Proteomes:UP000266272}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBT 40837 {ECO:0000313|EMBL:RFU81032.1,
RC ECO:0000313|Proteomes:UP000266272};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the eIF-2B alpha/beta/delta subunits family.
CC {ECO:0000256|ARBA:ARBA00007251, ECO:0000256|RuleBase:RU003814}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RFU81032.1}.
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DR EMBL; PXOA01000072; RFU81032.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395NY57; -.
DR STRING; 490622.A0A395NY57; -.
DR Proteomes; UP000266272; Unassembled WGS sequence.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04664; Nudix_Hydrolase_7; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR000649; IF-2B-related.
DR InterPro; IPR042529; IF_2B-like_C.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR43475; METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR43475:SF3; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_2G14290); 1.
DR Pfam; PF01008; IF-2B; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:RFU81032.1};
KW Protein biosynthesis {ECO:0000313|EMBL:RFU81032.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000266272}.
FT DOMAIN 4..153
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 509 AA; 56014 MW; 80068BC30D7FF6C7 CRC64;
MSQLKKSAVA VSFIFKFPDG NVSRRPQVAL FRRSGEVNTY RHKYAPISGG VEVTDANPLA
TAWRELREET TLTSTSLRLF RQGKPYSFTD AEVGRIWTIN PFSFILKSHQ EGGLGVEGIK
IDWEHEGYEW FDPDEVTDDG SSQGVPRLKE SLRRVWFDID LGKDAGSALA AGLRALQGDH
ESGARQLASK ALDIYLDVIS KVAAGDRDAW WKNVRFAGWH LWKNGRESMG APILSVILSS
LDIIEKKLQL LPHGTLSKDA IEQACSSIKH FGRTRQQSGS KIGNAFASFL NQHFPINDEP
VKIVTLSSSS TITSSISHIL SSASASHPLD IHILESRPLF EGVKVAQRIS SLLQTAKSNN
ATTITLHTDA SAALASQNAH VLLLGADLID KSGNVSNKTG SLPAVLAARH VSPKVKVVVL
SEKEKILPFE PPGHEENDSE ELVRVWGEVF DLGSETGLQD VNIKNVYFEW VPANLIDVYL
TEDGVEGTED VERWAGEVQQ KASHFFDDL
//
