ID A0A395RNJ8_9HYPO Unreviewed; 777 AA.
AC A0A395RNJ8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN ORFNames=FLONG3_10433 {ECO:0000313|EMBL:RGP61717.1};
OS Fusarium longipes.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=694270 {ECO:0000313|EMBL:RGP61717.1, ECO:0000313|Proteomes:UP000266234};
RN [1] {ECO:0000313|EMBL:RGP61717.1, ECO:0000313|Proteomes:UP000266234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 20695 {ECO:0000313|EMBL:RGP61717.1,
RC ECO:0000313|Proteomes:UP000266234};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC clathrin to receptors in coated vesicles. Clathrin-associated protein
CC complexes are believed to interact with the cytoplasmic tails of
CC membrane proteins, leading to their selection and concentration.
CC {ECO:0000256|PIRNR:PIRNR002291}.
CC -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGP61717.1}.
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DR EMBL; PXOG01000303; RGP61717.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395RNJ8; -.
DR STRING; 694270.A0A395RNJ8; -.
DR Proteomes; UP000266234; Unassembled WGS sequence.
DR GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR026739; AP_beta.
DR InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR PANTHER; PTHR11134:SF1; AP-3 COMPLEX SUBUNIT BETA; 1.
DR Pfam; PF01602; Adaptin_N; 1.
DR PIRSF; PIRSF002291; AP_complex_beta; 2.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR002291};
KW Protein transport {ECO:0000256|PIRNR:PIRNR002291};
KW Reference proteome {ECO:0000313|Proteomes:UP000266234};
KW Transport {ECO:0000256|PIRNR:PIRNR002291}.
FT DOMAIN 37..604
FT /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01602"
FT REGION 22..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 655..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..675
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..770
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 777 AA; 86200 MW; E47B1DEB8243F24D CRC64;
MESIARISGL METARELTLD AAQATRGART SSRPLDRSQM KKLLDSRNER EVLDGLRRVI
AMMYRNHKTL PFFSSVVKNV ASPNIEIKKL VYIYLIHHAE QEPDLALLSI NTIQKSLSDQ
NPQVRALALK TMSGIRVPVI SQIVSLAIKK GVADMSPYVR KAAALAIPKC HRLDPSQAPQ
LIENLSTLLG DKQYYVAGAA VSAFLEICPD RIDLIHKHYR TLIKQVVDMD EWSQLATLRL
MTYYARKCFP QKSKSSDEFT EIAQDQKVDD FYGESRQGGR GQGSSSVLDP DLALLLNGIR
PLLQSRNAGV VVAVTRCYVD IGTPEYVKQA IGPLIALLRG AQDIQQTALF NIVSVCLIRP
ADFVKYASHF LVRATDTAPI WELKLEILTI IFPHSPSHVK SLILKELEHF SQGTNKALVR
EAVRAIGRCA QTDTTTAPRC LKLLLGQITS LDGTLAAESL TVIRHLIQQD VQGHVGTVVR
LAKNLDSATD PQARATIIWL VGEFSGLNGE DNIAPDVLRI LLKEFTNESP VAKQQILLLA
AKVYLHHLNR KSEAEKEQDA EDDPPVETDT HPVVRLWEYA LLLVRYDTSF DLRDRARMYR
SLLAVPQLAT LMLLAEKPAP QAPSPSESRK GFLLGSSTLV LAGGGGVHGL RGYEPLPDWV
EEGQQPDRRL REPQGGQSSK YDSERSTLPA SDRLDEAAKT VMPSKANGTG EAVGTKTLDD
WLGEEQESEE SSEETEDESS EEEDDEEDEE EEEEETDSDD DDDDDDDDGE ADRLVKS
//
