ID A0A395RSP7_FUSSP Unreviewed; 662 AA.
AC A0A395RSP7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0000313|EMBL:RGP63178.1};
GN ORFNames=FSPOR_8760 {ECO:0000313|EMBL:RGP63178.1};
OS Fusarium sporotrichioides.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=5514 {ECO:0000313|EMBL:RGP63178.1, ECO:0000313|Proteomes:UP000266152};
RN [1] {ECO:0000313|EMBL:RGP63178.1, ECO:0000313|Proteomes:UP000266152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3299 {ECO:0000313|EMBL:RGP63178.1,
RC ECO:0000313|Proteomes:UP000266152};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGP63178.1}.
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DR EMBL; PXOF01000135; RGP63178.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395RSP7; -.
DR STRING; 5514.A0A395RSP7; -.
DR Proteomes; UP000266152; Unassembled WGS sequence.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046165; P:alcohol biosynthetic process; IEA:UniProt.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR GO; GO:0043386; P:mycotoxin biosynthetic process; IEA:UniProt.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 2.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001:SF72; THIJ_PFPI FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_3G01210)-RELATED; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR Pfam; PF19086; Terpene_syn_C_2; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 2.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000266152};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT COILED 616..643
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 662 AA; 75704 MW; 2A606A7132CE7A2E CRC64;
MANETFCEVE DISKYDTKGF FSGFKLLRSK FEWLANQAVY EFRLDWQHYV GDLASDYYGS
CNPINGNIFS LAHPLCRPER VKIATYVVEL GFFQDDVMEH TAKGHPQSQP YADDFSMGEA
EKVLGLRSGV KQLLAKLFLE LETIDPICSA PVIDKWKEWM TSQRELRPTF ESFDNYLDFR
VMDAANAFIA ALLLFGLGFT LTDEEHEMLA PIIHPCYAAL ALTNDYFSFN KECDESQKSK
DYEFTNATKV LMDLEGLDAD AAKDLVKQKA NSYAVRLCLY LDALSFEMMG NLIWNLNCPR
YHPENRYNDP NAGLENVMTA ELRGIAPSEG SPWHNKLLHS VWKHNEGTHE SPWSSPKASS
LCRYLKAPFE YISSCPGKGV RREFIDALNL WAKLPNDAIL GVQGVIDQLH IASLMIDDIQ
DGSKLRRGSP SAHEVFGIPQ TINATSFAII DAIEKARRLS IPHAADITTK QLHDIFIGQS
YDLYWTRHSI TPSESEYVQM VRKKTGGPFQ LITELMCHNL SEGLRGMLHE FVNVLAVFFQ
IRDDYQNLTS TEYTMKKGEL EDLDEGKFSF ILVHHFNSKP DRSIVYELLR QRHLQGGLSK
ASKLLIMDEL KRSKSIEYTL DTLKKLEEQC ENLLGKIEDI TQERNWVLRY LLHRLRLSSL
EA
//
