ID A0A395RZ19_FUSSP Unreviewed; 1583 AA.
AC A0A395RZ19;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Myosin myo2 {ECO:0000313|EMBL:RGP65049.1};
GN ORFNames=FSPOR_7439 {ECO:0000313|EMBL:RGP65049.1};
OS Fusarium sporotrichioides.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=5514 {ECO:0000313|EMBL:RGP65049.1, ECO:0000313|Proteomes:UP000266152};
RN [1] {ECO:0000313|EMBL:RGP65049.1, ECO:0000313|Proteomes:UP000266152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3299 {ECO:0000313|EMBL:RGP65049.1,
RC ECO:0000313|Proteomes:UP000266152};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGP65049.1}.
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DR EMBL; PXOF01000107; RGP65049.1; -; Genomic_DNA.
DR STRING; 5514.A0A395RZ19; -.
DR Proteomes; UP000266152; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006996; P:organelle organization; IEA:UniProt.
DR CDD; cd15480; fMyo2p_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.30.70.1590; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR046943; Fungal_Myo2/2A_CBD.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF706; MYOSIN-11; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 3.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 5.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF50084; Myosin S1 fragment, N-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000266152}.
FT DOMAIN 6..61
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 74..781
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1228..1497
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 188..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 656..678
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1107..1128
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 951..1079
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 168..175
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1583 AA; 180266 MW; 81EFFB8F3ADC0B58 CRC64;
MASAYEVGTR AWQPDTAEGW VASELINKTV DGSKVKLTFQ LENGDTKDIE VSAEALQSGS
DPSLPPLMNP TMLEASDDLT NLSHLNEPAV LQAIRLRYLQ KEIYTYSGIV LIATNPFARV
DSLYVPGMVQ VYAGRQRATQ APHLFAIAEE AFMDMIRDKK NQTVVVSGES GAGKTVSAKY
IMRYFATRES PDNPGGRSKR GSESMSETEE QILATNPIME AFGNAKTTRN DNSSRFGKYI
EIMFDEETNI IGAKIRTYLL ERSRLVFQPL KERNYHIFYQ LIAGASDQQR EELGLLPIEE
FEYLNQGNCP TIDGVDDKAE FEATQKSLST IGVTNEQQAD IFKLLAGLLH LGNVKITASR
NDSVLAPNEP SLEKACDILG VKAEEFSRWI VKKQLITRGE KITSNLSQAQ AIVVRDSVAK
FIYSSMFDWL VDIINTSLAS EDVLSRVTSF IGVLDIYGFE HFAKNSFEQF CINYANEKLQ
QEFNQHVFKL EQEEYLREQI DWTFIDFSDN QPCIDLIEGK LGILSLLDEE SRLPMGSDEQ
FVTKLHHNFT PDKSKFYKKP RFGKSAFTVC HYAIDVTYES EGFIEKNRDT VPDEHMAVLR
ASSNEFLKTV LDAATAVREK DAASSSSNAV KPAAGRKIGV AVNRKPTLGG IFRSSLIELM
STINNTDVHY IRCIKPNEAK EAWKFEGPMV LSQLRACGVL ETVRISCAGY PTRWTYEEFA
LRYYMLVRSD GWTSEIREMA DAILKKALGT STGKGLDKYQ LGLTKIFFRA GMLAFLENLR
TTRLNDCAIM IQKNLRAKYY RQRYLEAREA IILTQSAIRS WKARKQANEL RTVKAAITIQ
RVWRGSKQRK SYLQFRKDMV LFESIAKGYL RRKTILEERL GNAALKIQRS WRSRRQLMAW
RQYRKKVVLI QSLWRGRKAR KEYKTIREEA RDLKQISYKL ENKVVELTQS LGSMKERNKG
LASQVENYEG QIKSWKKRHN DLEARTKELQ TEANQAGIAV ARLQAMEDEM KKLQVAFDES
TANIKRMQEE ERELRESLRL TNTELETAKR SSTQHEKDNM SLRQELESLR DALELARRNA
PINGELANGT TPGATVPSGL INLVASKKPK RRSAGAEPRE LDRFSGTYNP RPVSMAVTGT
AHRQNLSGST FLPGVDNIEM ELETLLADED GLNEEVTMGL IRNLKIPSPS TTPPPSDKEV
LFPSYLINLV TSEMWNNGFV KESERFLANV MQSIQQEVMQ HDGDEAINPG AFWLSNVHEM
LSFVFLAEDW YEAQKSDNYE YDRLLEIVKH DLESLEFNIY HTWMKVLKKK LQKMIIPAII
ESQSLPGFVT NESSRFLGKL LQSNSTPAYS MDNLLSLLNS VFRAMKAYYL EDSIITQTIT
ELLKLVGVTA FNDLLMRRNF LSWKRGLQIN YNITRIEEWC KSHDMPEGTL QLEHLMQATK
LLQLKKATLN DIEIIQDICW MLSPNQIQKL LNQYLVADYE QPINGEIMKA VASRVTEKSD
VLLLQAVDMD DSGPYEIAEP RVITALETYT PSWLQTPRLK RLAEIVSAQA IAQQEKLDYT
DGEEYENGHQ HELEGVDEVE VEQ
//
