ID   A0A395S8U8_FUSSP        Unreviewed;       250 AA.
AC   A0A395S8U8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Aflatoxin biosynthesis ketoreductase nor-1 {ECO:0000313|EMBL:RGP68522.1};
GN   ORFNames=FSPOR_5260 {ECO:0000313|EMBL:RGP68522.1};
OS   Fusarium sporotrichioides.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX   NCBI_TaxID=5514 {ECO:0000313|EMBL:RGP68522.1, ECO:0000313|Proteomes:UP000266152};
RN   [1] {ECO:0000313|EMBL:RGP68522.1, ECO:0000313|Proteomes:UP000266152}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3299 {ECO:0000313|EMBL:RGP68522.1,
RC   ECO:0000313|Proteomes:UP000266152};
RX   PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA   Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA   Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA   Busman M., Gutierrez S.;
RT   "Evolution of structural diversity of trichothecenes, a family of toxins
RT   produced by plant pathogenic and entomopathogenic fungi.";
RL   PLoS Pathog. 14:e1006946-e1006946(2018).
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000256|ARBA:ARBA00006484}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RGP68522.1}.
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DR   EMBL; PXOF01000070; RGP68522.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A395S8U8; -.
DR   Proteomes; UP000266152; Unassembled WGS sequence.
DR   CDD; cd05325; carb_red_sniffer_like_SDR_c; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43544:SF26; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY OXIDOREDUCTASE (JCVI); 1.
DR   PANTHER; PTHR43544; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000266152}.
SQ   SEQUENCE   250 AA;  26765 MW;  11D5EE05748C7972 CRC64;
     MSTEAKNTIY VVTGANRGVG LGLVKTLLTR PSTTVIATVR NDTAAKNLQG ELSNVAASKD
     STFEVVQLDF SSSLPPEQIR NAIISKVDHV DILICNAAVS PPMTLAAQTP AEDLRTAFEV
     NTIGPLTVFQ GLWPLLQKSV APKLINMTSS VGCITFQEVP GGAYGPSKAA LNWITRALHI
     QNESLVAVAL HPGWVRTDMG EFSAREWGFP GAPMETVENS VQGILEVIDG ATRDTTSGKY
     VTYKGQILPW
//