ID A0A395SM98_FUSSP Unreviewed; 517 AA.
AC A0A395SM98;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Beclin 1 {ECO:0000313|EMBL:RGP73205.1};
DE Flags: Fragment;
GN ORFNames=FSPOR_2163 {ECO:0000313|EMBL:RGP73205.1};
OS Fusarium sporotrichioides.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=5514 {ECO:0000313|EMBL:RGP73205.1, ECO:0000313|Proteomes:UP000266152};
RN [1] {ECO:0000313|EMBL:RGP73205.1, ECO:0000313|Proteomes:UP000266152}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 3299 {ECO:0000313|EMBL:RGP73205.1,
RC ECO:0000313|Proteomes:UP000266152};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- SIMILARITY: Belongs to the beclin family.
CC {ECO:0000256|ARBA:ARBA00005965}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGP73205.1}.
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DR EMBL; PXOF01000029; RGP73205.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395SM98; -.
DR STRING; 5514.A0A395SM98; -.
DR Proteomes; UP000266152; Unassembled WGS sequence.
DR GO; GO:0006914; P:autophagy; IEA:InterPro.
DR Gene3D; 6.10.250.3110; -; 1.
DR Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR InterPro; IPR007243; Atg6/Beclin.
DR InterPro; IPR038274; Atg6/Beclin_C_sf.
DR InterPro; IPR041691; Atg6/beclin_CC.
DR InterPro; IPR040455; Atg6_BARA.
DR PANTHER; PTHR12768; BECLIN 1; 1.
DR PANTHER; PTHR12768:SF4; BECLIN-1; 1.
DR Pfam; PF04111; APG6; 1.
DR Pfam; PF17675; APG6_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000266152}.
FT DOMAIN 180..308
FT /note="Atg6/beclin coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF17675"
FT DOMAIN 311..507
FT /note="Atg6 BARA"
FT /evidence="ECO:0000259|Pfam:PF04111"
FT REGION 65..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 183..282
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 65..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RGP73205.1"
SQ SEQUENCE 517 AA; 57803 MW; 0AE57C6BC9A386DA CRC64;
LQLSKTSTSY RFQQRIQSTS ALISCAYRRR NMNCQKCRQP LRLDGSLEDL NPAAYDVLVA
SASPQTLKKS SVPNPPLAQP QDQSRKSLYD RVARNAGPPT FKRNHGSHPR DSSMSFVLLS
ESQMARPTPS SDPPTTPTVL RRASSSKSNA DNPDAPMGSE MDRINRLFAV LSARSDIDHP
ICVECTEMLV EGLQKKLEIA SRERDSYAKH LKEAKANKPS EEDMKVQEEA LRKAERDRAT
AMEELKKLES EKTSLDEELV LLEEESRQLD KEEEEFWRER NDFATRMADF QAERDSINAK
YSNDSQLLEK LQRSNVYNDT FCISHDGSFA TINGLRLGRL SNKPVDWPEI NAAWGHALLL
LVTVADKLAY RFDGYDPQPM GSTSKIIRYE VPSPSSSRLG SRAASVPPKK HVLELYSAGD
MPLGLTFMHR RFDNAMVGFL ELVRQLGAFV HRQTDATGTP LSLPYKIDGD KIGDVSIKLG
LTQDDGWTKA CKLTLTCCKF LLAHASNVTS NARNGGS
//
