ID A0A395STN3_9HYPO Unreviewed; 827 AA.
AC A0A395STN3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 03-MAY-2023, entry version 14.
DE RecName: Full=Probable vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|PIRNR:PIRNR007949};
GN ORFNames=FLONG3_5570 {ECO:0000313|EMBL:RGP75813.1};
OS Fusarium longipes.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium.
OX NCBI_TaxID=694270 {ECO:0000313|EMBL:RGP75813.1, ECO:0000313|Proteomes:UP000266234};
RN [1] {ECO:0000313|EMBL:RGP75813.1, ECO:0000313|Proteomes:UP000266234}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 20695 {ECO:0000313|EMBL:RGP75813.1,
RC ECO:0000313|Proteomes:UP000266234};
RX PubMed=29649280; DOI=10.1371/journal.ppat.1006946;
RA Proctor R.H., McCormick S.P., Kim H.S., Cardoza R.E., Stanley A.M.,
RA Lindo L., Kelly A., Brown D.W., Lee T., Vaughan M.M., Alexander N.J.,
RA Busman M., Gutierrez S.;
RT "Evolution of structural diversity of trichothecenes, a family of toxins
RT produced by plant pathogenic and entomopathogenic fungi.";
RL PLoS Pathog. 14:e1006946-e1006946(2018).
CC -!- FUNCTION: Essential for vacuolar protein sorting. Required for vacuole
CC biogenesis, stability and to maintain vacuole morphology.
CC {ECO:0000256|PIRNR:PIRNR007949}.
CC -!- SIMILARITY: Belongs to the VPS16 family.
CC {ECO:0000256|ARBA:ARBA00009250, ECO:0000256|PIRNR:PIRNR007949}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGP75813.1}.
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DR EMBL; PXOG01000120; RGP75813.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395STN3; -.
DR STRING; 694270.A0A395STN3; -.
DR Proteomes; UP000266234; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR016534; VPS16.
DR InterPro; IPR006925; Vps16_C.
DR InterPro; IPR038132; Vps16_C_sf.
DR InterPro; IPR006926; Vps16_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR Pfam; PF04840; Vps16_C; 1.
DR Pfam; PF04841; Vps16_N; 1.
DR PIRSF; PIRSF007949; VPS16; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|PIRNR:PIRNR007949};
KW Reference proteome {ECO:0000313|Proteomes:UP000266234};
KW Transport {ECO:0000256|PIRNR:PIRNR007949}.
FT DOMAIN 8..410
FT /note="Vps16 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04841"
FT DOMAIN 503..807
FT /note="Vps16 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04840"
FT REGION 805..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 92907 MW; 1226FE459AF50074 CRC64;
MDTLHARADW ESVGDRWFRK TQQYTAVFDQ DLDLDNYIVA GAPYAGALAL WRDDTKLLAY
QPGRSAKPAI DIYSLAGKKL RSIPWDKGSI KGLGWSEDET LLVVTADGTV RCYDLQGDFT
QFSLGHGADN YSVESCRFYD HGMVALLGNN SLITVSSYTE PRPKALAQTP EGEIHAWSII
SPNHTLSRSV EVLLSVEKTI YVVDATDCED RFLDIGPFSH ISVSPDGRYV NLYAMNGKAH
VISSDFQERL FEHDSNSQTP PLYVEWCGSD ALIAWEDEVH IIGPGDSSSS YIYDSTRVHV
VSEHDGARLI TNDFCEFLER VPRDTLEVFG QSSDSSPASI LLDAVGQLEL QSPKADDYIQ
LIRPNLTGAV DTCVNAAGRE FDTHWQKRLL KAASFGKSVL DIYNSDDFVD MCETLRVLNA
VRFYEVGMPL SFEQYHRLTP EALIRRLLNR HEYLLALKIA GYLKLPTDRI YVHWASSKVR
VGGEDDDTIC RLIVERLSGK PGISFEEIAR AAYQEGRGRL ATELLNHEPR GGRQVPLLLS
MEEDELALDK AVESGDTDLI LSVLLQLRKK LPLAAFFRVI NARPSATALV EALAMEEGDN
TLLKDLYYQD DRRTDGANVF IRESLKQPDA RTASDKLALA AKLLADSKES SFEVHALKEA
TTLLRMQEAF DRDLTDTFTG LSVNETMFKL IRLGYHGRAK KIQSEFKVPE KVAWWIRLRA
LVAKRDWNEI EEISKTRRSP IGWEPFFNLT LQAGNPRVAS VFVPKCTGLE TGETITMYEK
CGMRVKAAQE AVRLKDSESW ERILEDAGKG TQEGREIERL GQSAFKK
//
