ID A0A395YLT2_9CLOT Unreviewed; 364 AA.
AC A0A395YLT2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:RGZ00689.1};
GN ORFNames=DXA13_04515 {ECO:0000313|EMBL:RGZ00689.1};
OS Clostridium sp. AM58-1XD.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=2292307 {ECO:0000313|EMBL:RGZ00689.1, ECO:0000313|Proteomes:UP000266320};
RN [1] {ECO:0000313|EMBL:RGZ00689.1, ECO:0000313|Proteomes:UP000266320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AM58-1XD {ECO:0000313|EMBL:RGZ00689.1,
RC ECO:0000313|Proteomes:UP000266320};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RGZ00689.1}.
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DR EMBL; QSDR01000005; RGZ00689.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A395YLT2; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000266320; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000266320}.
FT DOMAIN 3..290
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 364 AA; 40284 MW; 8D7A15F0D34CCBDE CRC64;
METTIGFIGL GLIGGSIARG LKRSHPDIRV MAYMRTRSKL EQAQKDGIVD DILDGVDERF
GACSMIFLCT PVEYNAGYLS QLKPFLKPHT IVTDVGSTKT AIHEAVVSLS MEEWFIGGHP
MAGSEKTGYE NSTDHLLENA YYMITPSSRS TEDQISRLVA VAEALGSIPK VIDYHEHDFA
VAAISHLPHI VASSLVNLVR DSDSSEEIMK QIAAGGFKDI TRIASASPEM WEQICMTNTA
NIMDILEKYI HSLNIVLDQL KARNSEAVYR LFDSSRTYRN SISDVSRGAI EPEYAFSVDI
VDEVGSISTL SVILAAKGIS MKNIGINHSR EHGEGALRIA FYDEASMEAA WEQLTRYKYE
LMKM
//
