ID A0A396PVN4_9CLOT Unreviewed; 679 AA.
AC A0A396PVN4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=PTS maltose transporter subunit IICB {ECO:0000313|EMBL:RHV63658.1};
GN ORFNames=DXB18_13430 {ECO:0000313|EMBL:RHV63658.1};
OS Clostridium sp. OM02-18AC.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=2292311 {ECO:0000313|EMBL:RHV63658.1, ECO:0000313|Proteomes:UP000266676};
RN [1] {ECO:0000313|EMBL:RHV63658.1, ECO:0000313|Proteomes:UP000266676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OM02-18AC {ECO:0000313|EMBL:RHV63658.1,
RC ECO:0000313|Proteomes:UP000266676};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHV63658.1}.
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DR EMBL; QULW01000020; RHV63658.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A396PVN4; -.
DR Proteomes; UP000266676; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0008982; F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity; IEA:InterPro.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00212; PTS_IIB_glc; 1.
DR Gene3D; 2.70.70.10; Glucose Permease (Domain IIA); 1.
DR Gene3D; 3.30.1360.60; Glucose permease domain IIB; 1.
DR InterPro; IPR011055; Dup_hybrid_motif.
DR InterPro; IPR036878; Glu_permease_IIB.
DR InterPro; IPR018113; PTrfase_EIIB_Cys.
DR InterPro; IPR001127; PTS_EIIA_1_perm.
DR InterPro; IPR003352; PTS_EIIC.
DR InterPro; IPR013013; PTS_EIIC_1.
DR InterPro; IPR001996; PTS_IIB_1.
DR NCBIfam; TIGR00826; EIIB_glc; 1.
DR NCBIfam; TIGR00830; PTBA; 1.
DR PANTHER; PTHR30009; CYTOCHROME C-TYPE SYNTHESIS PROTEIN AND PTS TRANSMEMBRANE COMPONENT; 1.
DR PANTHER; PTHR30009:SF24; PTS SYSTEM, IIBC COMPONENT; 1.
DR Pfam; PF00358; PTS_EIIA_1; 1.
DR Pfam; PF00367; PTS_EIIB; 1.
DR Pfam; PF02378; PTS_EIIC; 1.
DR SUPFAM; SSF51261; Duplicated hybrid motif; 1.
DR SUPFAM; SSF55604; Glucose permease domain IIB; 1.
DR PROSITE; PS51093; PTS_EIIA_TYPE_1; 1.
DR PROSITE; PS00371; PTS_EIIA_TYPE_1_HIS; 1.
DR PROSITE; PS51098; PTS_EIIB_TYPE_1; 1.
DR PROSITE; PS51103; PTS_EIIC_TYPE_1; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphotransferase system {ECO:0000256|ARBA:ARBA00022683};
KW Sugar transport {ECO:0000256|ARBA:ARBA00022597};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 51..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..232
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 324..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..434
FT /note="PTS EIIC type-1"
FT /evidence="ECO:0000259|PROSITE:PS51103"
FT DOMAIN 446..528
FT /note="PTS EIIB type-1"
FT /evidence="ECO:0000259|PROSITE:PS51098"
FT DOMAIN 552..656
FT /note="PTS EIIA type-1"
FT /evidence="ECO:0000259|PROSITE:PS51093"
FT ACT_SITE 468
FT /note="Phosphocysteine intermediate; for EIIB activity"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00421"
SQ SEQUENCE 679 AA; 74303 MW; E8AF71800B22EA0E CRC64;
MKTFIQKLGK SLMGPLSIIV AAGLLLGLAS TLQNPNVFGN VLQDVAFVNN FVSLVNALAG
ALFGLLPILF CMSVAQGMSR EDREVATFAS IIGFALFHTT IRFFLSLKGI TADTVSIDYL
MRQGYSLLEA TQQNAAYDTV MGIFTYRMSI FGGIIVGLWT AMIHNRFHET QLPVAFSFFS
GKRFVPIMMV VTIPFLGLLM FFVWPVFNVI INGFGSLLAS AGAFGTFIYG FLERLLIPTG
LHHILNQLIR FTPIGGTAEI DGQQVSGALN IFNTLLMQQN PDMDVMRQAT RFLTQGTHPF
MVFGLPAACY AMYKTAYPQN REKAKGILLA AGLTSFFTGI TEPIEFSFIF ISPLLWVFHA
FMAGMSFLIN TFLSVCIGNA GGGLVDLMLF GVLRGPQTKW ILNVGVGLVY AVIYYNVFKW
AIVKFNIKTP GREDESDAVD YNEEITELGS AIMEALGGKE NIVEIDNCIS RLRLVLKDSA
KVNEKALKAT GSLGLIRINE ENVQVVYGAK VEKAAAELKR AVKKAGSSAA GKHADFEAPV
AGSLIPITEV KDTAFSQKMV GDGFAIIPES NTVYAPWSGT VAACFETNHA VGIVTENGDE
VLIHIGIDTV KLKGEGFRSF VKQGQKVKQG EKLIEFDREL IHSRGLDPVV ILIFPNKTVN
VNAAHQKLKE HQEINVKIY
//
