ID A0A396QCW7_9FIRM Unreviewed; 404 AA.
AC A0A396QCW7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=2-iminoacetate synthase ThiH {ECO:0000313|EMBL:RHV86854.1};
GN ORFNames=DXA96_14715 {ECO:0000313|EMBL:RHV86854.1};
OS Lachnospiraceae bacterium OF09-33XD.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=2292273 {ECO:0000313|EMBL:RHV86854.1, ECO:0000313|Proteomes:UP000265865};
RN [1] {ECO:0000313|EMBL:RHV86854.1, ECO:0000313|Proteomes:UP000265865}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OF09-33XD {ECO:0000313|EMBL:RHV86854.1,
RC ECO:0000313|Proteomes:UP000265865};
RA Zou Y., Xue W., Luo G.;
RT "A genome reference for cultivated species of the human gut microbiota.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHV86854.1}.
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DR EMBL; QUME01000031; RHV86854.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A396QCW7; -.
DR Proteomes; UP000265865; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR012726; ThiH.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR02351; thiH; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF1; 2-IMINOACETATE SYNTHASE; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00301; 2-iminoacetate_synthase_(ThiH); 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000265865};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 290..396
FT /note="Biotin and thiamin synthesis-associated"
FT /evidence="ECO:0000259|SMART:SM00876"
SQ SEQUENCE 404 AA; 46406 MW; 8C094D7352F67737 CRC64;
MSTDQINDSI FSDEIKEHLK ENRIDHMTYL PGMEDVGTDI QEQVISRMKD YDYDQYTEAD
VRRALSHERR TPEDFAALLS PAALSCLEEM AQRAREETRK HFGNSVYMFT PLYIANYCEN
YCIYCGFNCH NKIRRARLTP DEIRREMEAI SKTGLQEILI LTGESRAKSD VEYIGQACRI
AKDYFRVIGL EVYPMNSDEY AYLHQCGADY VTVFQETYDS DKYETLHLAG HKRIFPYRLN
AQERALQGGM RGVGFAALLG LTDFRKDAYA TGIHAWLIQR KYPHAEIAFS CPRLRPIINN
EKINPMDVHE RQLLQVVSAY RLFMPFASIT VSTRECARVR DNLVQIAATK ISAGVSTGIG
SHVEELEDKG DEQFEISDGR SVEEVFQALV QQDLQPVMAD YVYV
//
