ID   A0A397GFX3_9EURO        Unreviewed;       356 AA.
AC   A0A397GFX3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   22-FEB-2023, entry version 9.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
GN   ORFNames=CDV56_105090 {ECO:0000313|EMBL:RHZ49049.1};
OS   Aspergillus thermomutatus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=41047 {ECO:0000313|EMBL:RHZ49049.1, ECO:0000313|Proteomes:UP000215305};
RN   [1] {ECO:0000313|EMBL:RHZ49049.1, ECO:0000313|Proteomes:UP000215305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HMR AF 39 {ECO:0000313|EMBL:RHZ49049.1,
RC   ECO:0000313|Proteomes:UP000215305};
RA   Parent-Michaud M., Dufresne P.J., Fournier E., Martineau C., Moreira S.,
RA   Perkins V., De Repentigny L., Dufresne S.F.;
RT   "Draft genome sequence of azole-resistant Aspergillus thermomutatus
RT   (Neosartorya pseudofischeri) strain HMR AF 39, isolated from a human nasal
RT   aspirate.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHZ49049.1}.
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DR   EMBL; NKHU02000186; RHZ49049.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A397GFX3; -.
DR   STRING; 41047.A0A397GFX3; -.
DR   VEuPathDB; FungiDB:CDV56_105090; -.
DR   OrthoDB; 4403at2759; -.
DR   Proteomes; UP000215305; Unassembled WGS sequence.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF39; ADENOSINE DEAMINASE 2; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215305}.
FT   DOMAIN          166..304
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   356 AA;  40510 MW;  241B466BE300E050 CRC64;
     MDFMKSKLTI LPQESIRHEL GVDKIWRRFE ACFGPADTMV SYEPIVRTFY QKLFEGLADD
     GINWVEIRSG GSSGQLVHTG QEDIDPNLDV WWDVMIEEIE KFQATDKGKN FWGMKIALER
     KQRFPELFSG YNLVAQEDLG CLLSDLAPEL IWFQEQTEYL NLTIPFFFHA GETLGDGNST
     DYNLVDAILF NSRRIGHGFS LYKHPTLIDE VIEKAVMVEV CPISNEVLRL ATDILHHPLP
     VMIAYGVPTA ISNDDPAILG QDIAGLSYDF YQTIQGFDNI GLAGLGALAH NSLRWSNFED
     QSDADWLRDI DLAARGDGIK AQRIQYWNQQ WEEFCRWIVA EYGDKYPPAE VAQVAN
//