ID A0A397GQE6_9EURO Unreviewed; 724 AA.
AC A0A397GQE6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN ORFNames=CDV56_105068 {ECO:0000313|EMBL:RHZ50250.1};
OS Aspergillus thermomutatus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=41047 {ECO:0000313|EMBL:RHZ50250.1, ECO:0000313|Proteomes:UP000215305};
RN [1] {ECO:0000313|EMBL:RHZ50250.1, ECO:0000313|Proteomes:UP000215305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMR AF 39 {ECO:0000313|EMBL:RHZ50250.1,
RC ECO:0000313|Proteomes:UP000215305};
RA Parent-Michaud M., Dufresne P.J., Fournier E., Martineau C., Moreira S.,
RA Perkins V., De Repentigny L., Dufresne S.F.;
RT "Draft genome sequence of azole-resistant Aspergillus thermomutatus
RT (Neosartorya pseudofischeri) strain HMR AF 39, isolated from a human nasal
RT aspirate.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RHZ50250.1}.
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DR EMBL; NKHU02000164; RHZ50250.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397GQE6; -.
DR STRING; 41047.A0A397GQE6; -.
DR VEuPathDB; FungiDB:CDV56_105068; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000215305; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF343; FORK HEAD DOMAIN TRANSCRIPTION FACTOR SLP1-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000215305}.
FT DOMAIN 211..306
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 211..306
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 594..661
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..404
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..486
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 79498 MW; 812CF5D4A76B553B CRC64;
MNPTRSAPFV PPLSEPAAEY DKKVSQSHSQ RLGLSCPSSL PLQPPENVPS GQECILDPPL
SSAHRPSPMK TPRGLKTSLS GRRELGFIPI TAPAPPKFTT DSPAKRTPST TYPYATSSSS
AMPQSALFTT FPSVNHEKQS SKEKRQLAES CNDNLADFPE PSFTSKPLKR TLMDAAPLKE
RTIKKQKRED VDLARLPNPQ EMTPIEDDGT KPPYSYATLI GMSILRAPNR RLTLAQIYKW
ISDTFSYYKH SDPGWQNSIR HNLSLNKAFI KQERPKDDPG KGNYWAIEPG MEAQFLKDKP
LRRATMSSLP LPVTSQREPA HTQSSSTTTW AVPPPNHSLV PKSSKNVDLS SDATIPASDP
ALQDDTSDEG ANATTSQAPL RSSPPQPMRS SPPIAPPRFI RQGTPPTPAH PISSAIVPRS
RKRESTTMND SGYFSSLESS AMRPKKTGHI LTSDLDIDPP RIKRGRAEEE IARIRSSSHD
ISPRRPGMLK DAGVVIGSSP VRGEYVSMLP PPLTPVIKFK KPTKPPPSVS PNTNLRNHRK
KIQQMVNSPL KHLGLTDEDL PWSPAFRIQD ETYTPSDHLH ATFDVFAESA EEGISTPAYG
SPEKRSAKRA RMDPENHTGT VLADITSVSV NSKPGIQSLS SAKSKGPLFP ESPSKISEHG
RFGDATHDDF FSFHLFDESP VEVDGVDLLQ GFQKIGSSSK DESARSKSHT SRPQLNIRSN
TALF
//
