ID   A0A397HLS4_9EURO        Unreviewed;       664 AA.
AC   A0A397HLS4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 7.
DE   RecName: Full=Peptidase C14 caspase domain-containing protein {ECO:0000259|Pfam:PF00656};
GN   ORFNames=CDV56_102438 {ECO:0000313|EMBL:RHZ62536.1};
OS   Aspergillus thermomutatus.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX   NCBI_TaxID=41047 {ECO:0000313|EMBL:RHZ62536.1, ECO:0000313|Proteomes:UP000215305};
RN   [1] {ECO:0000313|EMBL:RHZ62536.1, ECO:0000313|Proteomes:UP000215305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HMR AF 39 {ECO:0000313|EMBL:RHZ62536.1,
RC   ECO:0000313|Proteomes:UP000215305};
RA   Parent-Michaud M., Dufresne P.J., Fournier E., Martineau C., Moreira S.,
RA   Perkins V., De Repentigny L., Dufresne S.F.;
RT   "Draft genome sequence of azole-resistant Aspergillus thermomutatus
RT   (Neosartorya pseudofischeri) strain HMR AF 39, isolated from a human nasal
RT   aspirate.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C14B family.
CC       {ECO:0000256|ARBA:ARBA00009005}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHZ62536.1}.
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DR   EMBL; NKHU02000036; RHZ62536.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A397HLS4; -.
DR   VEuPathDB; FungiDB:CDV56_102438; -.
DR   OrthoDB; 1785951at2759; -.
DR   Proteomes; UP000215305; Unassembled WGS sequence.
DR   GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   Gene3D; 3.40.50.1460; -; 1.
DR   InterPro; IPR011600; Pept_C14_caspase.
DR   PANTHER; PTHR48104:SF30; METACASPASE-1; 1.
DR   PANTHER; PTHR48104; METACASPASE-4; 1.
DR   Pfam; PF00656; Peptidase_C14; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000215305}.
FT   DOMAIN          24..303
FT                   /note="Peptidase C14 caspase"
FT                   /evidence="ECO:0000259|Pfam:PF00656"
SQ   SEQUENCE   664 AA;  73510 MW;  CC76F6814EEE51BB CRC64;
     MLADTSQPKP PNPTHDQEMR VKYYAILIGI DDYAEKPLKG CVRDVQAIKA CLESQLGGLV
     DIQMLTASPT NNTPNPPAGK DSTLCPTHAN VVASMGKCIS LARAGDFIYI HYSGHGTRKP
     PSGEFSNTST GDLALSLHTG GEEANGRHLW GFELATFLQR LVSKGVVATL VLDCCFAASV
     YRRDDPTVRF LHYQSDTESR PPLVLDQAGE TREYNRSSTE DRDVSMLPNW LINPDHYAVL
     AACGPHEEAR EPRFEGENRG ALSYLLLSVI RRVGLSAKHG DIYEHLRAKF HHHGFAQNPV
     LYGNRHQGFF GEARCDLAAV AVPITGNGKN GSFRVHAGQA HGVTDGDEFV LFSPSAAASD
     PPSRREPVLA VVSRTRALTS DLEVVDRSSS SRVRAGWMAS LRTRLALQKY PIRLDSGVHD
     WKDLTKHLDK QQLNVNTRAG NSVALFTLAL KDDREYRILD SSGRDIINLP RMPQDSTSVS
     QVVDILKHLT QFQLVQYLFP HDASASTLRG CFKTYISHNG RAFEPGGQIE IEHDSVAELV
     LENEGNTDLY FFIYNLGPCW QVENVHRGTY IVVSPRSRGG LFKHTAKKKL RVRIPDQMME
     NGHHSCKDIV KVFVTSQPTS FDVLELPKLG GRAKGTVSDR GNTRQDDLAE YWAAVNFSIC
     IVES
//