ID   A0A397IN90_9GLOM        Unreviewed;      1058 AA.
AC   A0A397IN90;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   22-FEB-2023, entry version 12.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   ORFNames=Glove_216g121 {ECO:0000313|EMBL:RHZ75216.1};
OS   Diversispora epigaea.
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC   Glomeromycetes; Diversisporales; Diversisporaceae; Diversispora.
OX   NCBI_TaxID=1348612 {ECO:0000313|EMBL:RHZ75216.1, ECO:0000313|Proteomes:UP000266861};
RN   [1] {ECO:0000313|EMBL:RHZ75216.1, ECO:0000313|Proteomes:UP000266861}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IT104 {ECO:0000313|EMBL:RHZ75216.1,
RC   ECO:0000313|Proteomes:UP000266861};
RA   Sun X., Fei Z., Harrison M.;
RT   "Genome and evolution of the arbuscular mycorrhizal fungus Diversispora
RT   epigaea (formerly Glomus versiforme) and its bacterial endosymbionts.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|ARBA:ARBA00009340, ECO:0000256|RuleBase:RU367072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RHZ75216.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; PQFF01000201; RHZ75216.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A397IN90; -.
DR   STRING; 1348612.A0A397IN90; -.
DR   Proteomes; UP000266861; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR024687; MMS19_C.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF12460; MMS19_C; 1.
DR   Pfam; PF14500; MMS19_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367072};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266861};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          41..301
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
FT   DOMAIN          555..1008
FT                   /note="MMS19 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12460"
SQ   SEQUENCE   1058 AA;  119292 MW;  973CB06003FCDF73 CRC64;
     MERLARSYMI TPNDATDDSG SIVSSIVQNI WSGQLSLLAF VTSLEEFLTS EESSIRAKGT
     GLLSAVLTEC PQEQVNLAAV NVLVDFYCER LSDTTCVPEL ILGLVSISQF NSFREECAIK
     VSKSIFSNLK VQNYQQTTRH GVFLIFDVLL HSHLNACKKL GTEFVKGFIQ AMDGEKDPRN
     LLLAFSLVKL IIKEFDISQH VEELFEVTFC YFPITFRPPP DDPYGITSDD LKISLRECLS
     ETPKFAKNAM PLFLEKLTSS SGNAKKDSME TLAACAPVYG TENIVPYIDD LWEYLKDEIF
     NAKDDSFEVI ALETIRSLVV TLSAGVIGKS DHLQQFLKTV VTECMENLKV PELKLSKPCG
     RILKYCAMAS DPSYNLIILA TLHGLFDQYG HSDLATRKKA ILEILMEFIV AAQNLYGTIE
     INNDSQIELD DDFSIPLISF KKDLLRMFSS ALMKTDEYSE LRLCGLRGLH GMILLKQFLS
     DHEIEDILKY FNQIILIQDN DQDIIKDTLK YLGDIAHYKP LTVLKITIPI FISQLPSDYE
     SLKLDNIHGT KYSKVLGAIS EISIERIIFE ALVPEILVKL DGVNTFSSNL SKEYIESLLH
     TLHTLFVKKS SLNHDDISKY ANILIPHLIA KCVGPTLEIR KNHDDKGEEY CDDVFCDLKI
     IQTIAGIISI VTKNMNSREQ TMFITQIFEL FTQGNLQFIP FSEIEKNKHV IAFNPLMIES
     SSAQKNLTLL FTAAVGYMRQ EVSCSIPNIP DFLSRIVNAS LISNNKIYQN SLAQLAASIL
     NKWNQENELE NFIKIHVMGE LVRYLPSHSS IGESESNRIA SLHIFVWLTK ALVLRTHPAG
     YECTNYIIEL FNDDTLGKKA SSDGFKIIIG DSDLLNKQSF AIIKILYKQR FFDYVMPKLV
     QGFTESSGDA KHNYLIALSN LLRNIPKQIL MSEISPVFPL LVHSLSLPDP DLKASTIDTF
     YLIALEMPHI ISEHVSTLIP LLLSLTNVED GNTIKVRVAA LQCLSVFPDT VPFDVLYPFK
     SKILRDLGDV LDDKKRIVRK EAVNCRSRWF LFTGPKSS
//