ID A0A397LDG1_9FLAO Unreviewed; 396 AA.
AC A0A397LDG1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Acetyl-CoA acyltransferase {ECO:0000313|EMBL:RIA10148.1};
GN ORFNames=OE09_2001 {ECO:0000313|EMBL:RIA10148.1};
OS Flavobacteriaceae bacterium MAR_2010_72.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1250029 {ECO:0000313|EMBL:RIA10148.1, ECO:0000313|Proteomes:UP000265779};
RN [1] {ECO:0000313|EMBL:RIA10148.1, ECO:0000313|Proteomes:UP000265779}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mar_2010_72 {ECO:0000313|EMBL:RIA10148.1,
RC ECO:0000313|Proteomes:UP000265779};
RA Teeling H.;
RT "A large-scale integrated study on North Sea by COGITO (Coastal Microbe
RT Genomic & Taxonomic Observatory).";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIA10148.1}.
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DR EMBL; QXCW01000002; RIA10148.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397LDG1; -.
DR OrthoDB; 9764892at2; -.
DR Proteomes; UP000265779; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR43853; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR PANTHER; PTHR43853:SF8; 3-KETOACYL-COA THIOLASE, PEROXISOMAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:RIA10148.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265779};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:RIA10148.1}.
FT DOMAIN 5..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..393
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 91
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 349
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 381
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 396 AA; 42430 MW; 60C4D8666371FA56 CRC64;
MKQAYIVKAY RTAVGKAPKG LFRFKRTDEL AAETIKFMMK ELPNLDTKRI DDVIVGNAMP
EGSQGLNMAR FISLIGLDSV DVPGVTVNRF CASGIETIGL ATAKIQAGMA DCIIAGGAES
MSAVPMTGFK PELNYDTVKA GHPDYYWGMG NTAEAVAKQF KVSREDQDEF AFNSHMKALK
AQAEKRFQDQ IVPIEVEQTF IDDNGKKATK SYIVSKDEGP RAGTSLEALA KLRPVFAANG
SVTAGNSSQM SDGAAFVMVM SEAMVKELGL EPIARLVNYA AAGVEPRIMG IGPVKAIPKA
LKQAGLQQSD LELIELNEAF ASQSLAVIRE LNLNPDIINV NGGAIALGHP LGCTGAKLSV
QLFDEMRKRN MKGKYGAVTM CVGTGQGACG IFEFLN
//
