ID A0A397NIV4_9SPHN Unreviewed; 891 AA.
AC A0A397NIV4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:RIA35443.1};
GN ORFNames=DFR49_4220 {ECO:0000313|EMBL:RIA35443.1};
OS Hephaestia caeni.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Hephaestia.
OX NCBI_TaxID=645617 {ECO:0000313|EMBL:RIA35443.1, ECO:0000313|Proteomes:UP000266568};
RN [1] {ECO:0000313|EMBL:RIA35443.1, ECO:0000313|Proteomes:UP000266568}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 25527 {ECO:0000313|EMBL:RIA35443.1,
RC ECO:0000313|Proteomes:UP000266568};
RA Goeker M.;
RT "Genomic Encyclopedia of Type Strains, Phase IV (KMG-IV): sequencing the
RT most valuable type-strain genomes for metagenomic binning, comparative
RT biology and taxonomic classification.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIA35443.1}.
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DR EMBL; QXDC01000006; RIA35443.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397NIV4; -.
DR Proteomes; UP000266568; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF141371; PilZ domain-like; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266568};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..160
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..198
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 309..362
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 394..527
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 536..787
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 891 AA; 95169 MW; A22877F3568079D9 CRC64;
MTDSVRRAMN IAASARENSV LLSLVDPGDA ASAFDHVQPV RQVGAVWPLA MIAQIVIVAA
CVAIATRAGH PALVPQILVE GGLAAAAGVV VFAVLKIGRW RGLAPHLQVR AIACAAVAMA
ASQLTLLQTT VALPPGPFQL ACFVAVAGAI GLSASALFAI RAAILGFAIG LAAVISWLSG
PSVATLLALG LLACLGLVTQ RLAALDHRIA DERAVHENEG RLASRLVAEF ESHGSGWFWQ
TDRQGRLTYL SDKVARQLVV DGVGPIGRML NAVFRMDGGA PDTERTLGFH LNSRTAFADY
SVAAIGRVGD SSGESAEGTD DAACWWSISG RPATDDRGRF VGFIGSGSDL TEKRRSDAEI
ARLARFDGLT GLANRQQMKR SLDQTLAQSR RAYRPTALFL LDLDRFKAVN DTLGHQTGDA
LLKQVAQRLQ RAIGDKGLVG RLGGDEFEVV LPAEINRDRL GELAKSVIGA LSQPYFIQGS
SISIGCSIGV AIAPEDGEDS ESLIRNADLA LYAAKADGRG IHRFYRAELL VGAQNRKALE
DDLRHALAQN QFHLAYQPVV STREERIVGY EALIRWEHPT RGAISPAEFI PVAEECGLIE
TIGEWVMRTA CDEAARWPEG VRVAVNVSPI QFANPALPAI VTNALARSGI APQRLELEIT
EGVFLDETAS SDQMFKSLKA IGVRLALDDF GTGYSSLGYL KKAPFDKIKI DQSFVRGAAI
AGNRNAAIIK AIVTLAETLG METTAEGVEL KDELALIRDL GCSHIQGYIY GKPARSEEVE
KQLGNGGKAS PVGYKVSRSP RARMLRSARI EGGGTAGEVR IRDISATGAM IDGIEAGDDA
IGVDLLIELL EDEMFPARLR WASDGKAGIE FVEHFNLERL NQPARGLRKA G
//
