ID A0A397T132_9GLOM Unreviewed; 892 AA.
AC A0A397T132;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Sodium/calcium exchanger protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C1645_766142 {ECO:0000313|EMBL:RIA92028.1};
OS Glomus cerebriforme.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Glomerales; Glomeraceae; Glomus.
OX NCBI_TaxID=658196 {ECO:0000313|EMBL:RIA92028.1, ECO:0000313|Proteomes:UP000265703};
RN [1] {ECO:0000313|EMBL:RIA92028.1, ECO:0000313|Proteomes:UP000265703}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM 227022 {ECO:0000313|EMBL:RIA92028.1,
RC ECO:0000313|Proteomes:UP000265703};
RA Morin E., San Clemente H., Chen E.C.H., De La Providencia I., Hainaut M.,
RA Kuo A., Kohler A., Murat C., Tang N., Roy S., Loubradou J., Henrissat B.,
RA Grigoriev I.V., Corradi N., Roux C., Martin F.M.;
RT "Comparative genomics reveals the genomic features of Rhizophagus
RT irregularis, R. cerebriforme, R. diaphanum and Gigaspora rosea, and their
RT symbiotic lifestyle signature.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIA92028.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QKYT01000137; RIA92028.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397T132; -.
DR STRING; 658196.A0A397T132; -.
DR Proteomes; UP000265703; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR GO; GO:0015369; F:calcium:proton antiporter activity; IEA:UniProt.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004713; CaH_exchang.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR InterPro; IPR005185; YccF.
DR PANTHER; PTHR31503:SF10; CATION_H+ EXCHANGER PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR31503; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
DR Pfam; PF03733; YccF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000265703};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 185..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..329
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..474
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 587..607
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 728..746
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 766..786
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 798..818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 838..856
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 863..882
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 183..233
FT /note="Inner membrane component"
FT /evidence="ECO:0000259|Pfam:PF03733"
FT DOMAIN 423..560
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 727..880
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 1..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 32..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 892 AA; 100298 MW; 4596E51C947B537C CRC64;
MSQDNQDIPP SQTSAIAGSN VDAEPSEGSH RILINDPSSS TNNNSKNNSK SHPTSPTSTM
PKLRQRKSYS NDDDNDDDND DSDSDDSKIR KRKNLRRRRR QTSLTSNTGD NVIDENQDEN
EGDENESDHE FTLKDRQEAI NFTHPFGLPI WKPALYKKSR SITRNADSAL HLTPSPKLYL
SPGNIIWAIC FGWWLALVSY ILSIITLLMP FGGWRYAKVF RELSYYIFWP FGKFVEKDED
WPDDTPHEQP TDYFNYHNSV ISGMDIEDET RPLLGNLYIN PRRNSRSESF DLSDKLDEIG
LSGIFYYILF FLVLAPTFLF ASALCWLSVF PLPMAKLIHE LLKHLKRSPL SLHFKSGSSR
AASRSVVLLC TYRAFGLQYY KYTYDGINII FINLMAIVFF VIIDDRFLKF RFPDTLFATE
EFIFALSLAS VIPLSYFIGA AVASISAQSS IGMGAVINAT FGSIIEIILY AMALNKGRGK
LTEGSIIGSF MAGVLLMPGV SMVSGGLKRK EQKFNSKSAG VTSTMLIMAI IGALTPTLFF
QTYAPYKMSC KTIPCGDGLL NTSCQRCEHS EVEPTETPLY KESVKPLMYI CAAILLLSYL
IGLWFSLRTH ASLVYHTPHP QERSQSIYQR LAPVNIIQQL LPQTPSFLHP HQDGQNPPPL
PRSYSVPNAT IPVQSIIVPN HENTINLAGV ANNLQNPQTT SFRSAHETEE EEIVHGHDSP
NWSKVKSVLI LLTCTAFYSF IAEILVENVG FVLKHINTTE KILGLTLFAL VPNVTEFLNA
MLFALYGNIA LSMEIGSAYA LQVCLLQIPA MVGYSAWINK DKNEVQQRGY TFTLVFPRWD
VFAVVFSVFL LTYTYIEGKS NYFKGSILIL SYMVLMAGFF YAPSSNYDSY DV
//
