ID A0A397UB62_9GLOM Unreviewed; 219 AA.
AC A0A397UB62;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=H/ACA ribonucleoprotein complex subunit 2 {ECO:0000256|RuleBase:RU366039};
DE AltName: Full=Nucleolar protein family A member 2 {ECO:0000256|RuleBase:RU366039};
GN ORFNames=C2G38_2048343 {ECO:0000313|EMBL:RIB04543.1};
OS Gigaspora rosea.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Diversisporales; Gigasporaceae; Gigaspora.
OX NCBI_TaxID=44941 {ECO:0000313|EMBL:RIB04543.1, ECO:0000313|Proteomes:UP000266673};
RN [1] {ECO:0000313|EMBL:RIB04543.1, ECO:0000313|Proteomes:UP000266673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM 194757 {ECO:0000313|EMBL:RIB04543.1,
RC ECO:0000313|Proteomes:UP000266673};
RA Morin E., San Clemente H., Chen E.C.H., De La Providencia I., Hainaut M.,
RA Kuo A., Kohler A., Murat C., Tang N., Roy S., Loubradou J., Henrissat B.,
RA Grigoriev I.V., Corradi N., Roux C., Martin F.M.;
RT "Comparative genomics reveals the genomic features of Rhizophagus
RT irregularis, R. cerebriforme, R. diaphanum and Gigaspora rosea, and their
RT symbiotic lifestyle signature.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Common component of the spliceosome and rRNA processing
CC machinery. {ECO:0000256|RuleBase:RU366039}.
CC -!- FUNCTION: Required for ribosome biogenesis. Part of a complex which
CC catalyzes pseudouridylation of rRNA. This involves the isomerization of
CC uridine such that the ribose is subsequently attached to C5, instead of
CC the normal N1. Pseudouridine ('psi') residues may serve to stabilize
CC the conformation of rRNAs. {ECO:0000256|RuleBase:RU366039}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604, ECO:0000256|RuleBase:RU366039}.
CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC {ECO:0000256|ARBA:ARBA00007337, ECO:0000256|RuleBase:RU366039}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIB04543.1}.
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DR EMBL; QKWP01002159; RIB04543.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397UB62; -.
DR STRING; 44941.A0A397UB62; -.
DR Proteomes; UP000266673; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1330.30; -; 1.
DR InterPro; IPR002415; H/ACA_rnp_Nhp2-like.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004037; Ribosomal_eL8-like_CS.
DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45.
DR InterPro; IPR018492; Ribosomal_eL8/Nhp2.
DR PANTHER; PTHR23105:SF54; H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR23105; RIBOSOMAL PROTEIN L7AE FAMILY MEMBER; 1.
DR Pfam; PF01248; Ribosomal_L7Ae; 1.
DR PRINTS; PR00881; L7ARS6FAMILY.
DR PRINTS; PR00883; NUCLEARHMG.
DR SUPFAM; SSF55315; L30e-like; 1.
DR PROSITE; PS01082; RIBOSOMAL_L7AE; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU366039};
KW Reference proteome {ECO:0000313|Proteomes:UP000266673};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW ECO:0000256|RuleBase:RU366039};
KW Ribosomal protein {ECO:0000313|EMBL:RIB04543.1};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW RNA-binding {ECO:0000256|RuleBase:RU366039};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 110..198
FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45"
FT /evidence="ECO:0000259|Pfam:PF01248"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..38
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 219 AA; 24924 MW; A3E388257161721A CRC64;
MPKEKKETKV KKEKKEKKEK KSHKEKREKE REKNKELTHE VGMIVEKLAA KTVEEAVTEK
APKKVSKTVT ETAAEIATTQ KDISMVVHYD LSALVSFASP LATEEFTLEL MQIVRKASRK
RHCRRGVKEV VKALKKGHKG LVVIAGDISP IDIITHIPIL CEDSSVPYIY IPSRADLGFA
CATKRPTSVV MIVPDQKDEE AFDYKEHYMT CYKKVKELE
//
