ID A0A397VG99_9GLOM Unreviewed; 838 AA.
AC A0A397VG99;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=DUF221-domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=C2G38_2176497 {ECO:0000313|EMBL:RIB21494.1};
OS Gigaspora rosea.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Diversisporales; Gigasporaceae; Gigaspora.
OX NCBI_TaxID=44941 {ECO:0000313|EMBL:RIB21494.1, ECO:0000313|Proteomes:UP000266673};
RN [1] {ECO:0000313|EMBL:RIB21494.1, ECO:0000313|Proteomes:UP000266673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM 194757 {ECO:0000313|EMBL:RIB21494.1,
RC ECO:0000313|Proteomes:UP000266673};
RA Morin E., San Clemente H., Chen E.C.H., De La Providencia I., Hainaut M.,
RA Kuo A., Kohler A., Murat C., Tang N., Roy S., Loubradou J., Henrissat B.,
RA Grigoriev I.V., Corradi N., Roux C., Martin F.M.;
RT "Comparative genomics reveals the genomic features of Rhizophagus
RT irregularis, R. cerebriforme, R. diaphanum and Gigaspora rosea, and their
RT symbiotic lifestyle signature.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIB21494.1}.
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DR EMBL; QKWP01000358; RIB21494.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397VG99; -.
DR Proteomes; UP000266673; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF143; PHOSPHATE METABOLISM PROTEIN 7; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000266673};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 416..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 625..642
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 649..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..164
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 188..356
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 367..640
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 746..812
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
SQ SEQUENCE 838 AA; 94263 MW; F5FC2CE382427A99 CRC64;
MTTNATQQTN TSAATSAFES AVIFNMAFTT AGFIVFDLIR KKSARIFEPR TYIIPKEKQS
PPVPNGFLKW VVPTLKTSDE KLIDRVGLDG YMFLRVILAF MKLFTAFSVI GIGVILPLNH
VGQSNQPGLE SFTIGNINDT KRLYAHVIAC YLFTAAILYM MYHEYYTYIR LRHEYLTTPE
HRISARATTI LILGIPRQLN NKTVLTNLYN VFPGGVKRIW LNSEPTKLID LTAKRMKVLN
KLEKAETVFL EKYLKYLAKD GGSGQEVEDG NKIPTSLRPT HKKIPLIGKK VDSIETYRNE
ISQLNKDIND LRTQSNFKPL DSAFIQFNDF VGAQLAATST IPRLTEISRE DVIWENLKVT
NPSRVIRKII SFSITATLII LWAIPVSFVA TISSLSTLKT VIPFLKPLVD KLSESAVGFI
EGVLPAIGLA LLMVCLPYIL RELSKLEGLI RHSDVMLSLQ GKYFFFLLVN VLLVTTTVNG
AAQVIPVIIN NPTSIIKSLA VNLPKASTFF LTYVLLKIST ASIEALQVGS LSLYLATKNF
LVKTPRQILH LETTLEYKDW GVTFPPHILI ASIGLVYSVI QPLILPFTAL HFALYYLAYR
YNFLYVYDQI YETNGNLFVH AMEQFFWGIF IFQLTLIGLM FLNDAHIPGV LAVILFIITI
SIVLGIRVYF QHNPKAAFLP ANLMGVIDMK TGQVVDFTKS TSSVTEDEKV DQGSKSKQIS
EKPLTDIDDE YTSPNVVHIK HGDSDKELER SVNAYTHPAL IVTNPLVWIP QDRTELYKEE
IKRCQDSGLN ATSRGAKINE KYKVEVDITE APNITDEFYV EEAESSDAMI RNTTNVID
//
