ID A0A397VJ01_9GLOM Unreviewed; 1213 AA.
AC A0A397VJ01;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=DNA mismatch repair protein {ECO:0000256|PIRNR:PIRNR037677};
GN ORFNames=C2G38_2176948 {ECO:0000313|EMBL:RIB21327.1};
OS Gigaspora rosea.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Glomeromycotina;
OC Glomeromycetes; Diversisporales; Gigasporaceae; Gigaspora.
OX NCBI_TaxID=44941 {ECO:0000313|EMBL:RIB21327.1, ECO:0000313|Proteomes:UP000266673};
RN [1] {ECO:0000313|EMBL:RIB21327.1, ECO:0000313|Proteomes:UP000266673}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOM 194757 {ECO:0000313|EMBL:RIB21327.1,
RC ECO:0000313|Proteomes:UP000266673};
RA Morin E., San Clemente H., Chen E.C.H., De La Providencia I., Hainaut M.,
RA Kuo A., Kohler A., Murat C., Tang N., Roy S., Loubradou J., Henrissat B.,
RA Grigoriev I.V., Corradi N., Roux C., Martin F.M.;
RT "Comparative genomics reveals the genomic features of Rhizophagus
RT irregularis, R. cerebriforme, R. diaphanum and Gigaspora rosea, and their
RT symbiotic lifestyle signature.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIB21327.1}.
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DR EMBL; QKWP01000367; RIB21327.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397VJ01; -.
DR STRING; 44941.A0A397VJ01; -.
DR Proteomes; UP000266673; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR CDD; cd03286; ABC_MSH6_euk; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR037677};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PIRNR:PIRNR037677};
KW DNA repair {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR037677};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR037677};
KW Reference proteome {ECO:0000313|Proteomes:UP000266673}.
FT DOMAIN 1030..1046
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..240
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..45
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..64
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 94..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 155..171
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1213 AA; 137281 MW; 0F5C6D6FEDED3ABD CRC64;
MPLAKKEVSL GSNSCDADTN PKQEKTSPVK KTQKTLFSFL GLPTPSTSRL DEDDIEKCET
QTREQEPSSP DTPATPTTDK LNASLTSSTD IDGSSSEKES EEPTVGRRTL RGRVKRKIII
SSDEESEDVV SSPLQKEAPS RRKKTKKNGD DEYNGDTCNE DSDDAAISDV VEESDYDDKK
SRSKNTKKTV NKTNKTSGNL NSAQNKLKAF ASNSAIRRGS SFSSTIHMTN SEKKKQRASD
FKAKNEERYS WLQEVRDADG NLEGSPDYDS RTLFIPRSAW DKFTPFEKQF WEIKSKHWDT
VVFFKKGKFY ELYERDADIG HKEFDLKLTD RVNMRMVGVP EMAFESWAAQ FIAKGHKVAK
VDQMETALGK EMREKASNVK EDRIIRRELT SVFTAGTIVE GGLLTNEMST YCMSIKESCP
TENAPPAFGI CFVDTATAEF HLASFLDDVD RTQFETLIMQ TKPKEIIYEK GMLSQLSKRI
LKDCTNRPIW TALKPESEFW DANTTRSQIR MSRYFSNNQN TSIAQNEVDN EGDVTMIDND
EGNKIETWPS AIQEALKDPL MLSALGGLLW YLRSLKLDAE LVSLQNFHIY DPICHNTSLV
LDGQTLANLE VFENSLDGST QGTVFQLLNR CITPFGKRTF KQWLCHPLRD IAAINARLDA
IEELNTVPDF QDIFLVNFSH FPDLERLISR IHAGTCKVRD FLHVLTSFEK LTDTMEKLGG
FANDFKSIRL KQLFESFPDL KPMLTHFNKA FDHEKAYKEG NLLPYPGVES DYDEIINRMA
EVNKQLDGHL EDSKKLLKTS KIVYKDIGKE LFQLEVPNTI KVPDHWQKLS RTQKVNRYWN
PTLQKLIRDF QEAKETQSSV LKSLQSRFYQ KFDAHYRNWL LAVKIVGEID CLLSLAKSSL
ALGEPRCRPQ FVSQEQSILE FEELRHPCFT AGAAFDFIPN DTFLGGDQPN MILLTGPNMG
GKSTLLRQNC VAIIMAQLGC YVPAKHCRMT PFDRIYTRIG ANDNILAGQS TFMVELSETS
KIIHEATPRS MVILDELGRG TSTFDGYAIA YSVLHYLATH IGCLGLFSTH YGMLTQEFAK
NPNIALKHMS CHVDQDRKEV TFLYKLVPGV CPKSYGMNVA NMAGVPRQIV DRAEVVAAKF
EQTSKLQDIL TANSSNLPIT TLCDFVYLLK SAARNGDSSK EIDGGALDNR ADYKKEERYT
RVLKTIIRGI KLM
//
