ID A0A397YFY7_BRACM Unreviewed; 764 AA.
AC A0A397YFY7; M4FCX8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Chloride channel protein {ECO:0000256|RuleBase:RU361221};
GN ORFNames=BRAA08T32994Z {ECO:0000313|EMBL:VDD03517.1}, BRARA_H00674
GN {ECO:0000313|EMBL:RID49910.1};
OS Brassica campestris (Field mustard).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3711 {ECO:0000313|EMBL:RID49910.1, ECO:0000313|Proteomes:UP000264353};
RN [1] {ECO:0000313|EMBL:RID49910.1, ECO:0000313|Proteomes:UP000264353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B-3 {ECO:0000313|Proteomes:UP000264353};
RA Bowman J., Kohchi T., Yamato K., Jenkins J., Shu S., Ishizaki K.,
RA Yamaoka S., Nishihama R., Nakamura Y., Berger F., Adam C., Aki S.,
RA Althoff F., Araki T., Arteaga-Vazquez M., Balasubrmanian S., Bauer D.,
RA Boehm C., Briginshaw L., Caballero-Perez J., Catarino B., Chen F.,
RA Chiyoda S., Chovatia M., Davies K., Delmans M., Demura T., Dierschke T.,
RA Dolan L., Dorantes-Acosta A., Eklund D., Florent S., Flores-Sandoval E.,
RA Fujiyama A., Fukuzawa H., Galik B., Grimanelli D., Grimwood J.,
RA Grossniklaus U., Hamada T., Haseloff J., Hetherington A., Higo A.,
RA Hirakawa Y., Hundley H., Ikeda Y., Inoue K., Inoue S., Ishida S., Jia Q.,
RA Kakita M., Kanazawa T., Kawai Y., Kawashima T., Kennedy M., Kinose K.,
RA Kinoshita T., Kohara Y., Koide E., Komatsu K., Kopischke S., Kubo M.,
RA Kyozuka J., Lagercrantz U., Lin S., Lindquist E., Lipzen A., Lu C.,
RA Luna E., Martienssen R., Minamino N., Mizutani M., Mizutani M.,
RA Mochizuki N., Monte I., Mosher R., Nagasaki H., Nakagami H., Naramoto S.,
RA Nishitani K., Ohtani M., Okamoto T., Okumura M., Phillips J., Pollak B.,
RA Reinders A., Roevekamp M., Sano R., Sawa S., Schmid M., Shirakawa M.,
RA Solano R., Spunde A., Suetsugu N., Sugano S., Sugiyama A., Sun R.,
RA Suzuki Y., Takenaka M., Takezawa D., Tomogane H., Tsuzuki M., Ueda T.,
RA Umeda M., Ward J., Watanabe Y., Yazaki K., Yokoyama R., Yoshitake Y.,
RA Yotsui I., Zachgo S., Schmutz J.;
RT "WGS assembly of Brassica rapa FPsc.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:VDD03517.1}
RP NUCLEOTIDE SEQUENCE.
RG Genoscope - CEA;
RA William W.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EnsemblPlants:Bra038948.1-P}
RP IDENTIFICATION.
RC STRAIN=cv. Chiifu-401-42 {ECO:0000313|EnsemblPlants:Bra038948.1-P};
RG EnsemblPlants;
RL Submitted (MAR-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361221}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361221}.
CC -!- SIMILARITY: Belongs to the chloride channel (TC 2.A.49) family.
CC {ECO:0000256|ARBA:ARBA00009476, ECO:0000256|RuleBase:RU361221}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU361221}.
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DR EMBL; CM010635; RID49910.1; -; Genomic_DNA.
DR EMBL; CM010635; RID49911.1; -; Genomic_DNA.
DR EMBL; LR031575; VDD03517.1; -; Genomic_DNA.
DR RefSeq; XP_009108066.1; XM_009109818.2.
DR STRING; 51351.M4FCX8; -.
DR EnsemblPlants; Bra038948.1; Bra038948.1-P; Bra038948.
DR GeneID; 103833748; -.
DR Gramene; Bra038948.1; Bra038948.1-P; Bra038948.
DR KEGG; brp:103833748; -.
DR eggNOG; KOG0474; Eukaryota.
DR HOGENOM; CLU_003181_4_0_1; -.
DR OMA; PIMITVM; -.
DR OrthoDB; 315083at2759; -.
DR Proteomes; UP000011750; Unassembled WGS sequence.
DR Proteomes; UP000264353; Chromosome a8.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:UniProtKB-UniRule.
DR CDD; cd04591; CBS_pair_voltage-gated_CLC_euk_bac; 1.
DR CDD; cd03685; ClC_6_like; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR002251; Cl_channel_pln.
DR PANTHER; PTHR11689; CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER; 1.
DR PANTHER; PTHR11689:SF92; CHLORIDE CHANNEL-LIKE PROTEIN CLC-G-RELATED; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR PRINTS; PR01120; CLCHANNELPLT.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR PROSITE; PS51371; CBS; 1.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Chloride {ECO:0000256|RuleBase:RU361221};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|RuleBase:RU361221};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361221};
KW Reference proteome {ECO:0000313|Proteomes:UP000011750};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361221};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361221}; Transport {ECO:0000256|RuleBase:RU361221}.
FT TRANSMEM 68..92
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 112..138
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 263..282
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 315..335
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 355..376
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 435..457
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 463..483
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 490..516
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT TRANSMEM 522..542
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361221"
FT DOMAIN 686..747
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 764 AA; 83903 MW; 33B1FBC3C7BB2AD5 CRC64;
MPDSTREDSV AVPLLPSLRH ATNSSSQVAI VGSNLCPVES LDYEIAENDF FKQDWRARSK
TQIFQYVFMK WLLCFFIGII VSLIGFTNNL AVENLAGVKF VVTSNMMLAG RYSMGFFVFT
VTNLILTLFA SVITAFVAPA AAGSGIPEVK AYLNGVDAPE IFSLRTLLVK IIGNISAVSG
SLLIGKAGPM VHTGACVASI LGQGGSKRYG LTWRWLRYFN NDRDRRDLVT CGSAAGIAAS
FRAPVGGVLF ALEEMSSWWR SALLWRIFFS TAVVAIVLRA LIDVCLSGKC GLFGKGGLIV
FDVYSENASY HLGDVLPVLL LGFVGGILGS IYNFLLEKVL RAYNYIYEKG VAWKIILACA
ISIFTSCLLF GLPFLASCQP CPADALEECP TIGRSGNFKK YQCPPGHYND LASLIFNTND
DAIKNLFSKN TDFEFHYLSV LVFFITCFFL SILSYGIVAP AGLFVPVIVT GASYGRFVGM
LLGSKNLNDG LYAVLGAASF LGGSMRMTVS LCVILLELTN NLLLLPMMMV VLLISKTVAD
AFNANIYNLI MKIKGFPYLH SHVEPYMRQL TVGDVVTGPL QVFKGIEKIE TIVHVLKTTN
HNGFPVVDGP PLAPASVLCG LILRDHILTL LKKRVFLSSP VAFDSNTLAQ FKADEFAKKG
SGRGDRIEDV ELSEEELNMY LDLHPFSNAS PYTVLETMSL AKALVLFREV GLRHILVIPK
LSNRPPLVGI LTRHDFMPEH ILGLRPSLSR SRWKRLRIRL PFLS
//
