ID A0A397ZIX7_BRACM Unreviewed; 1381 AA.
AC A0A397ZIX7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
GN ORFNames=BRARA_D00772 {ECO:0000313|EMBL:RID65587.1};
OS Brassica campestris (Field mustard).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3711 {ECO:0000313|EMBL:RID65587.1, ECO:0000313|Proteomes:UP000264353};
RN [1] {ECO:0000313|EMBL:RID65587.1, ECO:0000313|Proteomes:UP000264353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B-3 {ECO:0000313|Proteomes:UP000264353};
RA Bowman J., Kohchi T., Yamato K., Jenkins J., Shu S., Ishizaki K.,
RA Yamaoka S., Nishihama R., Nakamura Y., Berger F., Adam C., Aki S.,
RA Althoff F., Araki T., Arteaga-Vazquez M., Balasubrmanian S., Bauer D.,
RA Boehm C., Briginshaw L., Caballero-Perez J., Catarino B., Chen F.,
RA Chiyoda S., Chovatia M., Davies K., Delmans M., Demura T., Dierschke T.,
RA Dolan L., Dorantes-Acosta A., Eklund D., Florent S., Flores-Sandoval E.,
RA Fujiyama A., Fukuzawa H., Galik B., Grimanelli D., Grimwood J.,
RA Grossniklaus U., Hamada T., Haseloff J., Hetherington A., Higo A.,
RA Hirakawa Y., Hundley H., Ikeda Y., Inoue K., Inoue S., Ishida S., Jia Q.,
RA Kakita M., Kanazawa T., Kawai Y., Kawashima T., Kennedy M., Kinose K.,
RA Kinoshita T., Kohara Y., Koide E., Komatsu K., Kopischke S., Kubo M.,
RA Kyozuka J., Lagercrantz U., Lin S., Lindquist E., Lipzen A., Lu C.,
RA Luna E., Martienssen R., Minamino N., Mizutani M., Mizutani M.,
RA Mochizuki N., Monte I., Mosher R., Nagasaki H., Nakagami H., Naramoto S.,
RA Nishitani K., Ohtani M., Okamoto T., Okumura M., Phillips J., Pollak B.,
RA Reinders A., Roevekamp M., Sano R., Sawa S., Schmid M., Shirakawa M.,
RA Solano R., Spunde A., Suetsugu N., Sugano S., Sugiyama A., Sun R.,
RA Suzuki Y., Takenaka M., Takezawa D., Tomogane H., Tsuzuki M., Ueda T.,
RA Umeda M., Ward J., Watanabe Y., Yazaki K., Yokoyama R., Yoshitake Y.,
RA Yotsui I., Zachgo S., Schmutz J.;
RT "WGS assembly of Brassica rapa FPsc.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
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DR EMBL; CM010631; RID65587.1; -; Genomic_DNA.
DR Proteomes; UP000264353; Chromosome a4.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR45786; DNA BINDING PROTEIN-LIKE; 1.
DR PANTHER; PTHR45786:SF66; REPLICATION FACTOR-A CARBOXY-TERMINAL DOMAIN PROTEIN; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT DOMAIN 263..445
FT /note="Helitron helicase-like"
FT /evidence="ECO:0000259|Pfam:PF14214"
FT DOMAIN 1227..1258
FT /note="DNA helicase Pif1-like 2B"
FT /evidence="ECO:0000259|Pfam:PF21530"
SQ SEQUENCE 1381 AA; 158505 MW; 690046A0BBB1BFD8 CRC64;
MWYGERINNK KNTRKPKFAL CCGQGQVQLP LIYFRDNIRQ LNMVFSFTSL GGKCDRSVPK
GCGPLKMFVL QGENYHLMGS LKPPPGNTAK FGQLYIVDTE NEVTNRASII GKYKTASETS
KKETIRKQVI ESLLKMLNEV NPYVHQFRSA KDRFDTNPEE TFHMRIISSR AKDGRTYDTP
TASEVAALIL GDFNLDMDKR DIVLQEKQTG WLKRISEIHP SYLALQYPLI FTYGEDGFRL
EIKKRETEAT AKLKRQTISM RQWYAFRLQE RENECHTLLH SKRLFQQFLV DSYTSIESNR
LCYLRMNQKS LRSDTYDSIQ QAGNAGKKDL HDQGERFLLP ASFTGGPRYM KNNYMDAMAI
CKYFGFPDLF ITFTCNPKWP EITRYLQKRN LIADDRPDII GRIFKIKLDS LMIDLTDKEL
LGKTVSSMYT VEWQKRGLPH AHILLFMHPN SKFPTTDDID KVIVAEIPDK DKEPELYDII
KDMMIHGPCG AVNMNSPCML GSKTMYPKAY ADVTTVNKEG FPVYRRREQP GRFVEKKGFK
CDNRYVIPYN KDLSLRFRAH INVEWCNQTG SIKYLFKYIN KGQDRVTIAV EPPEKGSADQ
NISTNGKLKE KKKNEIKDFF NCRYVSACEG AWRTFMFHIH YRSTPVERLQ WHLEGKQIII
FKDDDTYEKV TSRKLIENTM FLGWFELNKV SAVARTLTLA EIPTRFTWNK KDKKFHDRKK
GFSIGRINYA PREIEDAFYC RVLLNIVRGP TCYEDIKTFR GVEYPSYKET CFAMGLLEDD
QEYIDDLKRA SFTGSASYLR QAFVIMLMSK SLSKPEVVWE ETWEFLAEDI EHKRRKLLHR
PDLSLSDAEK KQYALIEIEK LLKSNGTSLE KWKSMPKPIP DIVNNNVLIM DELSYDREEL
ESDLQRDIPK LTDEQKKIYD EITDAVFTKK GGVFFVYGFG GTGKTFLWRL LSAAVRVRSE
ICLNVASSGI ASLLLPGGRT AHSRFGIPIN PDEFSPCKLT QGTDKADLLK AASLIIWDEA
PMMSKHCFES LDRSMLDIVG DKDKRPFGGK VVVFGGDFRQ VLPVIHGAGR AEIVMAALNS
SYLWKHVKVL QLTKNMRLLS NNLSAEESKD LQEFSQWILD IGDGKIGDGN DGESLIDIPE
EFLILDAKDP IEAISSAVYG DATSLHQNNE AKFFQERAIL CPTNDDVNMI NQHMLDKLHG
EEKIFLSSDS IDASDRFSVN DQALTPDFLN RIKASGLPNH SLRLKVGCPV MLLRNIDPIT
EMYDFMIKAK VITGEKEKIG RTVLIPRLSI TPSDKKLPFK MRRRQLPISV AFAITINKSQ
GQTLSEVGIY LPRPVFSHGQ LYVAISRVTS KKGLKILIVD SEGKPQRQTK NVVFREIFDN
L
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