ID A0A397ZUD1_BRACM Unreviewed; 925 AA.
AC A0A397ZUD1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase {ECO:0000256|ARBA:ARBA00011982};
DE EC=3.2.2.6 {ECO:0000256|ARBA:ARBA00011982};
GN ORFNames=BRARA_C00933 {ECO:0000313|EMBL:RID68795.1};
OS Brassica campestris (Field mustard).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3711 {ECO:0000313|EMBL:RID68795.1, ECO:0000313|Proteomes:UP000264353};
RN [1] {ECO:0000313|EMBL:RID68795.1, ECO:0000313|Proteomes:UP000264353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B-3 {ECO:0000313|Proteomes:UP000264353};
RA Bowman J., Kohchi T., Yamato K., Jenkins J., Shu S., Ishizaki K.,
RA Yamaoka S., Nishihama R., Nakamura Y., Berger F., Adam C., Aki S.,
RA Althoff F., Araki T., Arteaga-Vazquez M., Balasubrmanian S., Bauer D.,
RA Boehm C., Briginshaw L., Caballero-Perez J., Catarino B., Chen F.,
RA Chiyoda S., Chovatia M., Davies K., Delmans M., Demura T., Dierschke T.,
RA Dolan L., Dorantes-Acosta A., Eklund D., Florent S., Flores-Sandoval E.,
RA Fujiyama A., Fukuzawa H., Galik B., Grimanelli D., Grimwood J.,
RA Grossniklaus U., Hamada T., Haseloff J., Hetherington A., Higo A.,
RA Hirakawa Y., Hundley H., Ikeda Y., Inoue K., Inoue S., Ishida S., Jia Q.,
RA Kakita M., Kanazawa T., Kawai Y., Kawashima T., Kennedy M., Kinose K.,
RA Kinoshita T., Kohara Y., Koide E., Komatsu K., Kopischke S., Kubo M.,
RA Kyozuka J., Lagercrantz U., Lin S., Lindquist E., Lipzen A., Lu C.,
RA Luna E., Martienssen R., Minamino N., Mizutani M., Mizutani M.,
RA Mochizuki N., Monte I., Mosher R., Nagasaki H., Nakagami H., Naramoto S.,
RA Nishitani K., Ohtani M., Okamoto T., Okumura M., Phillips J., Pollak B.,
RA Reinders A., Roevekamp M., Sano R., Sawa S., Schmid M., Shirakawa M.,
RA Solano R., Spunde A., Suetsugu N., Sugano S., Sugiyama A., Sun R.,
RA Suzuki Y., Takenaka M., Takezawa D., Tomogane H., Tsuzuki M., Ueda T.,
RA Umeda M., Ward J., Watanabe Y., Yazaki K., Yokoyama R., Yoshitake Y.,
RA Yotsui I., Zachgo S., Schmutz J.;
RT "WGS assembly of Brassica rapa FPsc.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + NAD(+) = ADP-D-ribose + H(+) + nicotinamide;
CC Xref=Rhea:RHEA:16301, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:17154, ChEBI:CHEBI:57540, ChEBI:CHEBI:57967; EC=3.2.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16302;
CC Evidence={ECO:0000256|ARBA:ARBA00000404};
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DR EMBL; CM010630; RID68795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A397ZUD1; -.
DR Proteomes; UP000264353; Chromosome a3.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR045344; C-JID.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR011713; Leu-rich_rpt_3.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF411; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE-RELATED; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF20160; C-JID; 1.
DR Pfam; PF07725; LRR_3; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
FT DOMAIN 58..222
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 28..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 925 AA; 104026 MW; B320A6BE71BE97A1 CRC64;
MDSSFFLTTV AAAIGLFTLL RKLRLHQDDN REKDSSSSSP SSSLSPSPVP PPSSPRIWTH
HVFPSFRGED VRKDFLSHIQ MEFQRKGITP FIDNEIKRGD DIGPELIRAI RGSKIAIILL
SRNYASSKWC LDELVEIMKC REELGQTVMA IFYKVDPSDV KKLAGDFGRV FKKTCAGRTK
ETIERWRQAL AKVATIAGYH SSNWDNEAAM IKKIATDISD MLNNFTPSND FDGLVGMGAH
LEKMEPLLCL GSDEVRMIGI WGPPGIGKTT IARVAYNQLS DSFQLSVFMD DIKGNYSRLC
SDDYSLKLQL QKQFMSQITN HKDMVVSHLG VASNRLKDKK VLVVLDGVDQ RHKVKIQHRG
DALQLTRGLN YISHKLRFLE WNYFPMTCLP SILNLEFLVE LIMHTSKLEK LWEGTKWMNL
RYSENLKELP DLSTATNLEL DLRNCSSLIK LPSLNGNSLE ILYIGRCSSL VEFPSFIENA
VSLRKLDLTS YPNLLELPSY VGNATNLDEL YLTNCLHLVE LPLSLGNLQK LKKLSLKGCS
KLEVFPTNIN LESLEKLDLA GCSSLDLGGC STIGNVPSLR MLKLRSLPQL LDLPSFIGNA
INLDYLDLSG CSNLVELPVF IGNLQKLKIL VLAGCSKLEF LPTNINLESL IFLSLSDCSM
LKCFPQISTN IRDLDLTGTA IEQVPPSIRS WPRLHTLHMS YFENLKEFPH ALERITSLCL
TDTEIQELPP WVKKISRLIE FVLKGCRKLV SIPPILDSIC YLDASDCESL EILECSFHNK
IITLNFANCF KLNQEARDLI IQNSVEAVLP GGQVPAYFTH QATGGGPLSI KLNEKPLPKS
LRFKACILLV DKGDHDACSK EKSTQVFAMY KNDRHMLCPA LAQHLYTFEV EKEVTSSELL
FEFKLESDDV WKIGECGIVQ HLEVP
//
