ID A0A398AL24_BRACM Unreviewed; 727 AA.
AC A0A398AL24;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=BRARA_A01263 {ECO:0000313|EMBL:RID78429.1};
OS Brassica campestris (Field mustard).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX NCBI_TaxID=3711 {ECO:0000313|EMBL:RID78429.1, ECO:0000313|Proteomes:UP000264353};
RN [1] {ECO:0000313|EMBL:RID78429.1, ECO:0000313|Proteomes:UP000264353}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. B-3 {ECO:0000313|Proteomes:UP000264353};
RA Bowman J., Kohchi T., Yamato K., Jenkins J., Shu S., Ishizaki K.,
RA Yamaoka S., Nishihama R., Nakamura Y., Berger F., Adam C., Aki S.,
RA Althoff F., Araki T., Arteaga-Vazquez M., Balasubrmanian S., Bauer D.,
RA Boehm C., Briginshaw L., Caballero-Perez J., Catarino B., Chen F.,
RA Chiyoda S., Chovatia M., Davies K., Delmans M., Demura T., Dierschke T.,
RA Dolan L., Dorantes-Acosta A., Eklund D., Florent S., Flores-Sandoval E.,
RA Fujiyama A., Fukuzawa H., Galik B., Grimanelli D., Grimwood J.,
RA Grossniklaus U., Hamada T., Haseloff J., Hetherington A., Higo A.,
RA Hirakawa Y., Hundley H., Ikeda Y., Inoue K., Inoue S., Ishida S., Jia Q.,
RA Kakita M., Kanazawa T., Kawai Y., Kawashima T., Kennedy M., Kinose K.,
RA Kinoshita T., Kohara Y., Koide E., Komatsu K., Kopischke S., Kubo M.,
RA Kyozuka J., Lagercrantz U., Lin S., Lindquist E., Lipzen A., Lu C.,
RA Luna E., Martienssen R., Minamino N., Mizutani M., Mizutani M.,
RA Mochizuki N., Monte I., Mosher R., Nagasaki H., Nakagami H., Naramoto S.,
RA Nishitani K., Ohtani M., Okamoto T., Okumura M., Phillips J., Pollak B.,
RA Reinders A., Roevekamp M., Sano R., Sawa S., Schmid M., Shirakawa M.,
RA Solano R., Spunde A., Suetsugu N., Sugano S., Sugiyama A., Sun R.,
RA Suzuki Y., Takenaka M., Takezawa D., Tomogane H., Tsuzuki M., Ueda T.,
RA Umeda M., Ward J., Watanabe Y., Yazaki K., Yokoyama R., Yoshitake Y.,
RA Yotsui I., Zachgo S., Schmutz J.;
RT "WGS assembly of Brassica rapa FPsc.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the transport of sterols.
CC {ECO:0000256|ARBA:ARBA00003361}.
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DR EMBL; CM010628; RID78428.1; -; Genomic_DNA.
DR EMBL; CM010628; RID78429.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A398AL24; -.
DR Proteomes; UP000264353; Chromosome a1.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd13294; PH_ORP_plant; 1.
DR Gene3D; 2.40.160.120; -; 1.
DR Gene3D; 3.30.70.3490; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR037239; OSBP_sf.
DR InterPro; IPR000648; Oxysterol-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10972; OXYSTEROL-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR10972:SF155; OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 2A; 1.
DR Pfam; PF01237; Oxysterol_BP; 1.
DR Pfam; PF15413; PH_11; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF144000; Oxysterol-binding protein-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 56..183
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 18..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 274..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 647..674
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 29..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 314..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 727 AA; 82533 MW; 12AC32233CE14CB8 CRC64;
MRVKELHPLC CITLESPHAL DDNKPPPEPV TNLTRSRSLP ATSLTGGSNR RSLASAGSVA
GILYKWTNFS KGWRSRYFLL RDGILSYSKI RRPENLNLLS SSDDVRLIGN ISADRLSRMD
SCSGRRKQEK SVGIVHLKVS SFRESKSDDR KFYIFTATKT LHLRTDSISD RAAWLQALAS
AKCIFPLRSL NGDFSFTSPK DLSISTERLK KRLQEAGMNE NLVKDCEQIM LSEFSEMHGQ
IKLLHEERTN LFDALRQLEE ANLEAGASGI HSSLGRGKYS ECSTTASSDD KQEFEDVSEE
DEPSFHDTKE YFNEPNVGSG SNLSNNSGYA DIKRRTKLPD PAEKEKAVSL WSMIKDNVGK
DLTRVCLPVY FNEPISSLQK CFEDLEYSYL LDRAYEHGKS GNGLLRALNV AAFAVSGYAS
TEGRHCKPFN PLLGETYEAD FPEKGIRFFS EKVSHHPTVI ANHCEGKGWK FWGDTNLRSK
FWGRSIQVEP VGVLTLEFDD GEVFQWSKVT STIYNIILGK LYCDHHGVMQ IRGNRQHSCT
LKFKEQSILE RNPHQVNGFV EDVAGQKAAT VFGKWDDSLY YVAGDGVSKT KVSDPASNAS
LLWRRTKPPL NVTRYNLTSF AITLNELTPG LKEMLPPTDS RLRPDQRHLE NGEYEKANLE
KQRLERRQRM SRQLQESGWR PRWFDKQGEN ETFKYTGGYW EARGHRKWDD CPNIFGEFTE
EQLADSA
//
