ID   A0A398BBF5_9BACI        Unreviewed;       728 AA.
AC   A0A398BBF5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=MMPL family transporter {ECO:0000313|EMBL:RID87499.1};
GN   ORFNames=D1970_04820 {ECO:0000313|EMBL:RID87499.1};
OS   Mesobacillus zeae.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Mesobacillus.
OX   NCBI_TaxID=1917180 {ECO:0000313|EMBL:RID87499.1, ECO:0000313|Proteomes:UP000265816};
RN   [1] {ECO:0000313|EMBL:RID87499.1, ECO:0000313|Proteomes:UP000265816}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JJ-247 {ECO:0000313|EMBL:RID87499.1,
RC   ECO:0000313|Proteomes:UP000265816};
RA   Seuylemezian A., Vaishampayan P.;
RT   "Bacillus jemisoniae sp. nov., Bacillus chryseoplanitiae sp. nov., Bacillus
RT   resnikiae sp. nov., and Bacillus frankliniae sp. nov., isolated from Viking
RT   spacecraft and associated surfaces.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RID87499.1}.
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DR   EMBL; QWVT01000009; RID87499.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A398BBF5; -.
DR   OrthoDB; 2365435at2; -.
DR   Proteomes; UP000265816; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000265816};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        193..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        250..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..316
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        383..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        552..569
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        576..598
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        610..631
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        652..675
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        681..703
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          581..709
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   728 AA;  79891 MW;  D70A3CF05BF12573 CRC64;
     MLTVMKKLTS LASSKKGAKW TLAIWVLASV LLGGFAPSAK EFATSINATG LPSDAKSLIA
     EKKVYEYFPD EKGTPAILVF NKKTALTQEE MKIIDGVSKK IEDEKIAAVK KVVPLYKMPP
     VAKTSFVSEN KTTVLLPVSL KDNLEREVIN ETIKDLEKLG KDELKAADAV SLKITGPAGI
     VSDMISIFSN ADIVLLLGTV GLIFVLLILI YRSPILSIVP LIAAGIVYEV VNKTIGLFGE
     GGMGIESQSL SIMSILLFAA LTDYALLILS RFREELRKEE NKYVAMKRCM EEVTEPIFFS
     GSTVLASMLV LFAAIYEPYR NFAPVFSIAM VLILLGGLTL LPALFVLLGR KSFWPIIPKV
     GSAAKGSATI WEKLAKNVVK RPIVGALIVF IPLLLLALNT LNVQYSFNLI KSFPDDIQSR
     QGYHILEDNF SPGDLAPATV IVEGKDQLES SDIKKLREEL LDHEGVASVT PELSAQNGPM
     QNTWLSEDGT EAKLTLTFKG SPYEKAALNE LSQLREDSGK IVEDAGLEGA KLYYSGETAK
     QLDTREANSR DTWVLVTLIT ILITVLLFIQ TKSYIAPLYM ILTIIFSYFT ALGTGSLIFD
     KIFGFEEISY RIPLYSFIFL VALGVDYNIM LISRIKEEAR RYPIKKAIEE GLAHTGGVIS
     SAGLILAATF GVLVTQPIME LYMFGATVAI GVLIDTFLIR TVLVPAIMVK LGKYSLWPLK
     VQEEKSCQ
//