ID A0A398CFW7_9BACL Unreviewed; 247 AA.
AC A0A398CFW7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=glucose-1-phosphate thymidylyltransferase {ECO:0000256|ARBA:ARBA00012461};
DE EC=2.7.7.24 {ECO:0000256|ARBA:ARBA00012461};
GN ORFNames=D3H35_15100 {ECO:0000313|EMBL:RIE02086.1};
OS Cohnella faecalis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX NCBI_TaxID=2315694 {ECO:0000313|EMBL:RIE02086.1, ECO:0000313|Proteomes:UP000266340};
RN [1] {ECO:0000313|EMBL:RIE02086.1, ECO:0000313|Proteomes:UP000266340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K2E09-144 {ECO:0000313|EMBL:RIE02086.1,
RC ECO:0000313|Proteomes:UP000266340};
RA Zhu H.;
RT "Cohnella cavernae sp. nov., isolated from a karst cave.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate +
CC dTDP-alpha-D-glucose; Xref=Rhea:RHEA:15225, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:37568, ChEBI:CHEBI:57477,
CC ChEBI:CHEBI:58601; EC=2.7.7.24;
CC Evidence={ECO:0000256|ARBA:ARBA00001095};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the glucose-1-phosphate thymidylyltransferase
CC family. {ECO:0000256|ARBA:ARBA00010480}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIE02086.1}.
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DR EMBL; QXJM01000039; RIE02086.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A398CFW7; -.
DR OrthoDB; 9803871at2; -.
DR Proteomes; UP000266340; Unassembled WGS sequence.
DR GO; GO:0008879; F:glucose-1-phosphate thymidylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR InterPro; IPR005907; G1P_thy_trans_s.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43532; GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43532:SF1; GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE 1; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Capsid protein {ECO:0000313|EMBL:RIE02086.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000266340};
KW Virion {ECO:0000313|EMBL:RIE02086.1}.
FT DOMAIN 2..233
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 247 AA; 26963 MW; 31D19E229331DB27 CRC64;
MKGIILAGGT GSRLFPLTKV TNKHLLPVGK YPMIFHAVFK LKQAGIQDIL IVTGKEHMGD
VVNLLGSGKE MGVSFTYKVQ DEAGGIAEAL GLAEQFVGAE PMVVVLGDNV FSDDISGYLT
NFKKQRSGAK ILIQEVADPQ RYGVPELHGD RIVSIEEKPA IPKSNFAVTG IYMYDNSVFE
IIKNLRPSGR GELEITDVNN AYIASNQLSY DILVGWWTDA GTHASWAKAN ELAQDIVYGE
EFGKIKE
//
