ID A0A398CLS0_9BACL Unreviewed; 1024 AA.
AC A0A398CLS0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D3H35_13515 {ECO:0000313|EMBL:RIE01808.1};
OS Cohnella faecalis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX NCBI_TaxID=2315694 {ECO:0000313|EMBL:RIE01808.1, ECO:0000313|Proteomes:UP000266340};
RN [1] {ECO:0000313|EMBL:RIE01808.1, ECO:0000313|Proteomes:UP000266340}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K2E09-144 {ECO:0000313|EMBL:RIE01808.1,
RC ECO:0000313|Proteomes:UP000266340};
RA Zhu H.;
RT "Cohnella cavernae sp. nov., isolated from a karst cave.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIE01808.1}.
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DR EMBL; QXJM01000039; RIE01808.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A398CLS0; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000266340; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 2.
DR InterPro; IPR011623; 7TMR_DISM_rcpt_extracell_dom1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR43047:SF83; HISTIDINE KINASE; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF07695; 7TMR-DISM_7TM; 1.
DR Pfam; PF02518; HATPase_c; 2.
DR Pfam; PF06580; His_kinase; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 2.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 2.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Reference proteome {ECO:0000313|Proteomes:UP000266340};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 210..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 305..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 436..654
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 692..809
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 920..1016
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT MOD_RES 742
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1024 AA; 115173 MW; CD3D4D9F4637CE66 CRC64;
MNKQLAVLLG MIGIFFIVTL IFIWDWLNPP GEFPEARNGV LDARQWDFAE QGVIPLSGQW
EFYEGQLLGP DDFRSGWKSM QARPQLVKVP GSWQRAVNSV RGEGFGAGTY RLLVDVNRED
IYSLRAKKIR LSSHIYINGT DVGGTGRPAL TAEDFVPSNV PFFGTAAANA GQVEIIMQVA
SFEFFQGGLV QAPIFGLTGD VMADRDNSRL ADMILITTLL VFGLYYVGMF KQWRKEPHIM
YFSLFCLSTG LFFSLDDEIL ATTLIPSLSF PWLQKMIFIF PYMTFLFFFR YVYSYLGEKE
STFIRLLRQF SYMYLALAVI VPNSYLTRLF SLGIALQILC FFAIFYAIFH SRRRETHGGY
YVTLGVFFLI FTWIYGQFRY LLALDNPYYI IVTPLLLVFS QAFLMSDRIR DAFQRSDRLT
TRLLQYDRQK DEFLATTSHE IRTPLHGIIN LSQALLDNQD TPLRPEHREN IQLLHLIGRR
LAGLVHDILD MNRIRYGQLS IHPTAVNVGT SVRFVMETLS VSSINREVKL VSELPRKLPL
VRADENRLRQ ILHNLMENGL KYTDRGTVKI SAEVREDELA LTVEDTGRGI PTDAFADLFQ
PFVQYQEDSS GSRDGIGLGL SISKQLVELQ GGRLEVESEV GVGSRFTFTL PIAHSEEEAA
ATTEWTGTGA AAEETTAPLS GSLQGGKAAE FHILIVDDEP SNLKVLIDAV TSMRHAYTAV
GSGREALDTL LRAPKPDLVL LDLMMPGLSG LEVCREIRSL RGLAELPVLM LTASGQTGDI
LASFNAGAND IVQKPFEMAE LKARVRSLLA MKNSSEQAIR REMDFLQAQI TPHFLYNSLN
ALVGLSYKDV DKLRETIHHL TTYLRGKFTF VFQGEFVAFE REMELVQAYL AIEQLRFGSR
LRVRYRNEDE IRCLLPPLTL QPIVENAVRH GIGQKPSGGT IDISVSRSTD GVEIIVEDDG
VGMDDDALRS LNKGGASGVG IGNVNRRLQM LYGRKLEIRS SPGQGTQVKL VIPEDNYVER
NIDR
//
