ID A0A399ESF1_9DEIN Unreviewed; 1137 AA.
AC A0A399ESF1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Cyclic di-GMP phosphodiesterase response regulator RpfG {ECO:0000313|EMBL:RIH85979.1};
DE EC=3.1.4.52 {ECO:0000313|EMBL:RIH85979.1};
GN Name=rpfG_3 {ECO:0000313|EMBL:RIH85979.1};
GN ORFNames=Mrose_01981 {ECO:0000313|EMBL:RIH85979.1};
OS Calidithermus roseus.
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Calidithermus.
OX NCBI_TaxID=1644118 {ECO:0000313|EMBL:RIH85979.1, ECO:0000313|Proteomes:UP000265341};
RN [1] {ECO:0000313|EMBL:RIH85979.1, ECO:0000313|Proteomes:UP000265341}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 110900 {ECO:0000313|EMBL:RIH85979.1,
RC ECO:0000313|Proteomes:UP000265341};
RA Da Costa M.S., Albuquerque L., Raposo P., Froufe H.J.C., Barroso C.S.,
RA Egas C.;
RT "Meiothermus roseus NBRC 110900 genome sequencing project.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00169}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIH85979.1}.
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DR EMBL; QWLA01000035; RIH85979.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A399ESF1; -.
DR OrthoDB; 23815at2; -.
DR Proteomes; UP000265341; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0071111; F:cyclic-guanylate-specific phosphodiesterase activity; IEA:UniProtKB-EC.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 4.
DR CDD; cd00156; REC; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00277; HDIG; 1.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF13185; GAF_2; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF08447; PAS_3; 3.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 2.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 4.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 4.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:RIH85979.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265341};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 3..117
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT DOMAIN 119..177
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 190..242
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 236..308
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 364..429
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 489..559
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 563..613
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 946..1137
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 1137 AA; 127951 MW; 507685CB046C6DEA CRC64;
MARILLVEDD QADLLLIRQH LEGLEAEWHS VGDLQALKRA LEKGPYDVML LSLGPRPEDG
LEELRVMRAY APDTPLVMLV PPRLEPLAMA VAKPDLDEFV VKRKGKLPGL RAAVEKALER
KHRRDLFEAV PVGLYRSTPE GRILEANPAL CAMLGYSREE LLGLDARALY LEAEEREAAV
AHLETTPLVV AQRLRLQRKD GEVLWVEEHA HAVRDSQGQV LYLEGSLVDI SERTRLEERF
RALVENTSDL IYLMDENGAM LYASPNVRQV LGYDPQGYLR ERLSVLSFVH PEDRPYAEAS
LEDLVRHPGQ TREYRLRILD ASGEVRHARV WGRNLLHDPA VRGIVLNVRD VTEEDRLRLS
LERERSRFKA IVEALSGVVF QVALLPGQPG RPVYVSPQAQ TVLGHSPEAL LENPALWWGN
VHPEDQASLP KDAGAPGEVR VLRYRYRHGQ SGAWVWIQEH RVADPEGQFL TGYAYDATKE
LEAQRALAEQ EALFRTLSET APALILLWQE EQLVFANREA ERTTGYSLEE LKSRPIWEFV
HPLDREMVRA RGQARLRGEA VESRYRFRIR TKSGETRWLD YSAARVDFGG RPAVLGVGFD
VTEAQEHQLD LEAVVRLAEA LRRSDELKVM LVAALDETLA LLDTPVGSVL LYDPESHSLE
EVASRGWLAP IPTPPVVQEE SLTGWVLLHG VPYVSREFAA DPKLRPAIRH LVPPGWGGVV
LPLRAGSWRV GALTLAVAHP RELSARELKR LELIGEAIGN AVRRASLRRK LEARVGQLEA
LRAIDQAISA SLDLRLALEV FCEQLMRLPL DAVSLLLYRK ESRMLETIET RGFRSPPSEV
RRLSVPLGQG HTGRAALERR PVGVDDLTRD PGFAPEFTLR EGFVAMRALP LLAKGELLGV
LVAFTRRPWD LSSEEEEFLE ALATQGSIAI ENSRLFEGLQ RAKLELELAY DLTLLGWAQA
VEMRDQETAG HTQRVTELTL KLARQMGLPE EDLEHLRRGA ILHDVGKLGV PDAVLLKPGS
LSEEEWALMR KHPTLAHQWL SGIPFLRKAL AIPYAHHERW DGSGYPRGLK GEAIPLEARI
FAVIDVYDAL TSDRPYRPAW PREKALEYIR EQSGKQFDPE VVAAFLELMH AEDSSAR
//
